Cross-Coupling of Aryl Iodides with Malononitrile Catalyzed by Palladium N-Heterocyclic Carbene Complex System  

作　　者：高诚伟 陶晓春 刘涛平 黄吉玲 钱延龙 

出　　处：《Chinese Journal of Chemistry》2002年第9期819-821,共3页中国化学（英文版）

摘　　要：Eight N heterocyclic carbenes (NHC), generated in situ from their imidazolium salts, as ligands of palladium complexes were used for the catalytic coupling of iodobenzene with malononitrile anion. It was found that 1,3 bis(2,4,6 trimethylphenyl) imidazolium chloride (IMesHCl) Pd 2(dba) 3 catalytic system has the highest activity to obtain phenyl malononitrile among the imidazolium salts. The substituted iodoarenes reacted with malononitrile anions by using the catalytic system to give cross coupling products in yields from 50% to 96%.Eight N heterocyclic carbenes (NHC), generated in situ from their imidazolium salts, as ligands of palladium complexes were used for the catalytic coupling of iodobenzene with malononitrile anion. It was found that 1,3 bis(2,4,6 trimethylphenyl) imidazolium chloride (IMesHCl) Pd 2(dba) 3 catalytic system has the highest activity to obtain phenyl malononitrile among the imidazolium salts. The substituted iodoarenes reacted with malononitrile anions by using the catalytic system to give cross coupling products in yields from 50% to 96%.

关 键 词：palladium complex N    heterocyclic carbene imidazolium salt cross  coupling arylmalononitrile 

分 类 号：O625[理学—有机化学]