广州地区中老年人群骨量减少及骨质疏松患病率的调查  

Prevalence rate of osteopenia and osteoporosis in middle-aged and elderly population in Guangzhou

作　　者：区品中[1] 邓力平[1] 刘毅生[1] 马翰章[1] 沈怀亮[1] 林秀娟[1] 刘红光[1] 刘兴漠[1] 

机构地区：[1]广州医学院第二附属医院,广州510620

出　　处：《中国骨质疏松杂志》2002年第4期314-317,354,共5页Chinese Journal of Osteoporosis

基　　金：国家"九五"科技攻关课题

摘　　要：目的　了解广州地区中老年人骨量减少 (Osteopenia)及骨质疏松 (Osteoporosis,OP)患病率的变化规律 ,为防治OP提供科学依据。方法　居住广州市内及郊区农村 2 0年以上的 40岁以上人群进行整群随机抽样 ,样本共 1 1 60人 ,准确记录其性别和年龄后 ,用美国Lunar公司的DEXA测试受试者L2 -4 和髋部的骨密度 (BMD) ,然后进行统计、比较与分析。结果　 40岁组女性L2 -4 及Ward’s区BMD高于男性 ,该组骨量减少患病率男女性都超过样本数的 1 3。 50岁以后男性高于女性 ,男性 70岁组L2 -4 下降才明显。女性L2 -4 及髋部BMD从 50岁起加速下降 ,L2 -4 BMD 70岁以后减慢。男性 60岁以后髋部BMD下降明显 ,不论男、女性髋部BMD下降直到 80岁以上都较显著。骨质疏松患病率随年龄的增长而增加 ,女性 50岁组起变化开始明显 ,60岁组OP患病率 85 % ,并一直以重度OP占多数。农村患病率高于城市。男性在 70岁组起OP患病率显著上升。结论　广州地区中老年人骨量减少及OP患病率与北京、上海、成都等地区近似。老年女性以重度OP占多数 ,50岁以上男性OP患病率达到 30 % 。Objective\ To investigate the regularities of prevalence rate of osteopenia and osteoporosis (OP) in the middle\|aged and the elderly in Guangzhou and to provide scientific basis for prevention of OP. Methods\ 1 160 random samples were obtained from people over 40 years of age who have been in Guangzhou city or outskirts over 20 years. Their sex and age were correctly recorded. BMD of L 2-4 and upper femur were examined by DEXA, then were compared with each other and were statistically analyzed. Results\ BMD of L 2-4 and Ward's triangle of the female was higher than that of the male in the 40\|year\|old group.Prevalence rate of osteopenia exceeded 35% of the samples of that group. BMD decreased with age, but BMD of the female decreased faster than that of the male. BMD of the male was higher than that of the female after 50 years of age. Prevalence rate of OP increased with age; moreover, there was rapid increase after 50 years of age in the female and most of them were severe OP cases. Prevalence rate of the male increased significantly in 70\|year\|old group. Conclusion\ The prevalence rate of OP and osteopenia in Guangzhou is similar to those in Beijing, Shanghai and Chengdu. Severe OP exists preclominantly in old females, and the prevalence rate of OP in male's over 50 years of age is about 30%, which deserves considerable attention.\;

关 键 词：广州地区 调查 骨密度 骨量减少 骨质疏松 患病率 OP 中老年人 

分 类 号：R681－31[医药卫生—骨科学]