1285例TGAb、TMAb阳性的甲状腺相关疾病分析  

Analysis of 1285 positive Cases of TGAb and TMAb urith Thyreid Disease

作　　者：耿峻[1] 李红萍 钟伟[1] 吴兴勇[1] 鄢良春[1] 

机构地区：[1]四川省内江市第一医院核医学科,四川内江641000

出　　处：《成都军区医院学报》2002年第3期4-5,共2页

摘　　要：目的 探讨抗甲状腺球蛋白抗体(TGAb)和甲状腺微粒体抗体(TMAb)的测定对甲状腺相关疾病诊断的临床意义。方法 对1285例TGAb、TMAb阳性检测者,结合其T_3、T_4、TSH值的不同变化,进行分析。结果 TGAb、TMAb阳性伴甲亢、甲低、甲功正常的例数比例为49.49％、36.49％、14％,而双侧甲状腺肿伴功能亢进和桥本氏甲状腺炎的TGAb、TMAb阳性增高的比率值有显著性差异。结论 TGAb、TMAb阳性结合T_3、T_4、TSH值测定,对甲状腺相关疾病的病因诊断和指导临床用药有重要价值。Objective To discuss the clinical value of TGAb and TMAb tested in diagnosis of thyroid disease.Methods 1285 positive cases of TGAb and TMAb were divided into three groups,based on the different changes ofT_3, T_4 and TSH (normal,above,below). The percentage of thyroid disease of these three groups was compared. Re-sults The percentage of positive TGAb and TMAb with hyperthyroidism and hypothyroidiation and normal were49. 49%,36. 49% and 14% respectively. There is a significant differece of positive ration of TGAb and TMAb be-tween hyperthyroidism and Haschimoto' s thyroiditis. Conclusion It is of important value to test TGAb and TMAbcombined with T_3, T_4 andTSH in diagnosis and therapy of thyroid disease.

关 键 词：甲状腺球蛋白抗体 甲状腺微粒体抗体 TGAB TMAB 甲状腺 诊断 

分 类 号：R581[医药卫生—内分泌]