盐酸左氧氟沙星注射液与五种止血药配伍的稳定性考察  

Study on compatible stability of levofloxicin hydrochloride injection with five kinds of hemostatic

作　　者：汤永玖[1] 汪凤梅[1] 虞和永[1] 

机构地区：[1]浙江大学医学院附属妇产科医院,杭州310006

出　　处：《中国现代应用药学》2002年第5期417-419,共3页Chinese Journal of Modern Applied Pharmacy

摘　　要：目的 :研究盐酸左氧氟沙星注射液与五种止血药 (酚磺乙胺、氨甲环酸、氨基己酸、氨甲苯酸注射液和注射用蛇毒血凝酶 )配伍的稳定性。方法 :采用紫外分光光度法考察盐酸左氧氟沙星与上述五种止血药配伍后室温下 3h内的含量变化情况 ,并进行了外观观察、pH值测量。 结果 :在室温条件下 ,盐酸左氧氟沙星注射液与上述药物配伍后含量和 pH值都有不同程度的变化。结论OBJECTIVE:To study the compatible stability of levofloxicin hydrochloride injection with five kinds of homostatic(etamsylate, tranexamic acid , aminocaproic acid , aminome thylbenzoic acid , hemocoagulaser). METHOD:Investigation of compatible content of levofloxicin with above mentioned five kinds of hemostatic, and determination pH of compatible solution in ambient temperature within 3h by ultraviolet spectrophotometry and pH meter.RESULTS:The content of levofloxicin and pH of compatible solution varies in different degrees. CONCLUSION:It is not suitable for levofloxicin hydrochloride injection to mix with above mentioned five kinds of hemostatic.

关 键 词：盐酸左氧氟沙星注射液 止血药 稳定性 

分 类 号：R978.19[医药卫生—药品] R942[医药卫生—药学]