枳实导滞浓缩丸质量标准研究  

Studies on Quality Control Standard of Zhishidaozhi Tabloid Pills

作　　者：刘友平[1] 宋英[2] 秦春梅[1] 张家明[2] 

机构地区：[1]成都中医药大学,四川成都610075 [2]成都中医药大学附属医院,四川成都610075

出　　处：《中国中药杂志》2002年第11期838-840,共3页China Journal of Chinese Materia Medica

摘　　要：目的 :建立枳实导滞浓缩丸的质量标准。方法 :采用TLC对处方中的大黄、枳实、黄连、黄芩进行定性鉴别 ;用HPLC法测定方中君药大黄中大黄素的含量。结果 :在TLC色谱中 ,能检出大黄、枳实、黄连、黄芩 ;大黄素在 0 .0 6 12～ 0 .6 12 0 μg与峰面积积分值呈良好的线性关系 ,r =0 .9999,平均回收率 97.9% ,RSD =2 .1%。结论 :所建立的方法对方中 4味药材能准确、快速地进行定性、定量检测 ,可用于枳实导滞浓缩丸的质量控制。Objective:To develop the quality control standard of Zhishidaozhi Tabloid Pills. Method: Applying TLC to indentify Radix et Rhizoma Rhei,Fructus Aurantii Immaturus,Rhizoma Coptidis ,Radix Scutellariae ,and HPLC to determine the content of emodin of Radix et Rhizoma Rhei. Result:Radix et Rhizoma Rhei ,Fructus Aurantii Immaturus,Rhizoma Coptidis and Radix Scutellariae could be indentified by TLC. Emodin showed a good linear relationship at a rang of 0.0612～0.612 μg, r=0.9999. The average recovery was 97.9 %, and RSD was 2.1%. Conclusion:The methods are accurate and quick ,and can be used for the quality control of Zhishidaozhi Tabloid Pills.

关 键 词：质量标准 枳实导滞浓缩丸 TLC HPLC 大黄素 

分 类 号：R286[医药卫生—中药学]