安易醒治疗苯二氮类药物中毒的疗效及经济学研究  

CLINICAL RESEARCH AND ECONOMIC ANALYSIS OF TREATMENT TO BENZODIAZEPINES POISONING BY ANEXATE

作　　者：许树耘[1] 周亚雄[1] 代小松[2] 

机构地区：[1]四川大学华西医院急诊科,四川成都610041 [2]四川省人民医院内科,四川成都610072

出　　处：《华西药学杂志》2002年第5期378-379,共2页West China Journal of Pharmaceutical Sciences

摘　　要：目的　评价安易醒疗效及经济学效果。方法　 86例苯二氮类药物中毒患者随机分为试验组和对照组 ,分别采用安易醒及传统治疗 ,评价不同时间点患者精神状态 ,以清醒改善程度判断临床疗效 ,并以成本—效果分析判断经济学效果。结果　 32 0min时完全清醒患者试验组为 95 .5 % ,对照组为 66 .7%两组有显著差别(P <0 .0 5) ;总成本两组有显著差别 (P <0 .0 5) ,试验组总成本低于对照组。结论　安易醒是疗效确切。OBJECTIVE To evaluate the clinical and economic effects of Anexate in treating drug overdose with benzodiazepines.METHODS Eighty-six patients were randomly divided into test group and control group.The test and control groups received Anexate and conventional therapy,respectively. Patients' mental status were assessed at different time.The clinical and economic effects were evaluated by cost-effective analysis CEA. RESULTS There were significant difference(P<0.05)between two groups in awakening patients at 320 minutes which was 95.5% for test group and 66.7% for control group.The cost of test group is lower than the control group,which also had significant difference (P<0.05). CONCLUSION It is efficient and safe for Anexate to treat overdose with benzodiazepines.

关 键 词：安易醒 苯二氮ZHUO 中毒 经济学 

分 类 号：R459.7[医药卫生—急诊医学] R97[医药卫生—治疗学]