2012～2015年我国≥35岁人群血脂异常状况调查  

Status of Dyslipidemia Among Adults Aged 35 Years and Above in China

作　　者：李苏宁 张林峰[1] 王馨[1] 陈祚[1] 董莹[1] 郑聪毅[1] 王佳丽[1] 亢玉婷 王增武[1] 朱曼璐[1] 高润霖[1] LI Suning;ZHANG Linfeng;WANG Xin;CHEN Zuo;DONG Ying;ZHENG Congyi;WANG Jiali;KANG Yuting;WANG Zengwu;ZHU Manlu;GAO Runlin(Division of Prevention and Community Health,National Center for Cardiovascular Diseases and Fuwai Hospital,CAMS and PUMC,Beijing(102308),China)

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心阜外医院社区防治部

出　　处：《中国循环杂志》2019年第7期681-687,共7页Chinese Circulation Journal

基　　金：国家“十二五”科技支撑计划项目“中国重要心血管病调查及关键技术研究”(2011BAI11B01);公益性行业科研专项“西藏与新疆地区慢性心肺疾病现状调查研究”(201402002)

摘　　要：目的:了解我国≥35岁人群血脂异常患病率,以及知晓、治疗和控制状况。方法:2012~2015年在我国东中西部不同地区采用分层多阶段随机抽样方法选取29 678名≥35岁人群纳入分析。根据2016年中国成人血脂异常防治指南所定义,甘油三酯(TG)≥2.26 mmol/L为高TG血症;总胆固醇(TC)≥6.22 mmol/L为高TC血症;高密度脂蛋白胆固醇(HDL-C)<1.04 mmol/L为低HDL-C血症;低密度脂蛋白胆固醇(LDL-C)≥4.14 mmol/L为高LDL-C血症;有以上情况之一者或区/县级以上医院诊断,目前服用调脂类药物,为血脂异常。根据2010年人口资料计算加权率。结果:我国≥35岁人群血脂异常患病率为34.7%,高TG、高TC、低HDL-C、高LDL-C血症患病率分别为14.1%、7.5%、19.2%和6.0%。血脂异常患病率在城市和农村居民之间差异无统计学意义(35.7%vs 34.1%,P=0.691),男性高于女性(40.0%vs 29.3%,P<0.001)。东部、中部和西部血脂异常患病率分别为33.8%、34.9%和35.8%,差异无统计学意义(P=0.905)。高血压、糖尿病合并血脂异常患病率分别为41.3%、53.1%。血脂异常者、高血压合并血脂异常者、糖尿病合并血脂异常者知晓率分别为16.1%、23.7%、27.2%,治疗率分别为7.8%、13.0%、16.4%,控制率分别为4.0%、6.5%、7.0%。结论:我国≥35岁人群血脂异常、高血压伴血脂异常和糖尿病伴血脂异常患病率较高,血脂异常知晓、治疗和控制率较低,血脂异常的防治工作亟待加强。Objectives:The current study was aimed to determine the prevalence,awareness,treatment and control status of dyslipidemia among adults aged≥35 years old across China.Methods:A total of 29,687 participants aged≥35 years old were involved in the current study,with a stratified multistage random sampling method in eastern,central and western regions of China.Hypertriglycerdemia(HTG)was defined as triglycerides≥2.26 mmol/L,hypercholesteremia(HTC)as total cholesterol≥6.22 mmol/L,low level of high density lipoprotein cholesterol(HDL-C)as HDL-C<1.04 mmol/L,and high level of low density lipoprotein cholesterol(LDL-C)as LDL-C≥4.14 mmol/L.Dyslipidemia was defined as anyone above,or history diagnosed by county level hospital,or taking lipid-lowing drugs.The rates of dyslipidemia were standardized by sex and age from 2010 population census data.Results:Among participants aged≥35 years old,the prevalence was 34.7%for dyslipidemia,14.1%for HTG,7.5%for HTC,19.2%for low HDL-C,and 6.0%for high LDL-C.No significant difference was observed in the prevalence of dyslipidemia between rural and urban population(35.7%vs 34.1%,P=0.691).However,the prevalence of dyslipidemia was higher in male than female(40.0%vs 29.3%,P<0.001).The prevalence in eastern,middle and western region were 33.8%,34.9%and 35.8%,respectively(P=0.905).The prevalence of dyslipidemia was 41.3%and 53.1%among patients with hypertension or diabetes mellitus,respectively.The rates for awareness were 16.1%among participants with dyslipidemia,23.7%among participants with dyslipidemia and hypertension,and 27.2%among participants with dyslipidemia and diabetes,respectively;the treatment rates were 7.8%,13.0%,and 16.4%,respectively;the control rates were 4.0%,6.5%,and 7.0%,respectively.Conclusions:The prevalence of dyslipidemia,as well as dyslipidemia and hypertension,or dyslipidemia and diabetes,among≥35 years old was high,however,the awareness rate and control rate were still low.The prevention and treatment for dyslipidemia remained challenging in China.

关 键 词：血脂异常 患病率 控制率 中国 知晓率 

分 类 号：R541[医药卫生—心血管疾病]