腹膜透析相关性腹膜炎致病菌、药敏及临床转归分析  

Analysis on pathogenic bacteria, drug sensitivity and clinical outcome of peritoneal dialysis-associated peritonitis

作　　者：邓金秀 王福珍 丘昭文 郭春花 林冲云 吴森超 DENG Jinxiu;WANG Fuzhen;QIU Zhaowen;GUO Chunhua;LIN Chongyun;WU Sengchao(Department of Nephrology,the 1st Hospital of Longyan affiliated to Fujian Medical University,Fujian Longyan 364000,China)

机构地区：[1]福建医科大学附属龙岩第一医院肾内科

出　　处：《上海医药》2019年第15期40-44,共5页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:探讨持续非卧床腹膜透析(CAPD)患者腹膜透析相关性腹膜炎(PDAP)发生的相关因素、分析腹膜炎的致病菌特点、药物敏感性和临床转归。方法:回顾性分析2012年5月至2017年10月福建医科大学附属龙岩第一医院肾内科收治的168例次PDAP患者的病原学、病原学特点、疗效以及转归。结果:PDAP最主要的相关因素是操作污染。168例次PDAP中132例次培养结果阳性。其中革兰阳性菌78例次(59.09%)、革兰阴性菌31例次(23.48%)、真菌14例次(10.6%)、混合感染9例次(6.82%)。结论:PDAP的发生率与操作不规范、营养不良密切相关,病原学仍以革兰阳性菌为主,真菌感染患者退出率高。Objective:To investigate the factors related to the occurrence of peritoneal dialysis-associated peritonitis(PDAP)in patients undergoing continuous ambulatory peritoneal dialysis(CAPD),and analyze their pathogenic bacteria,drug sensitivity and clinical outcome.Methods:The etiology,pathogenic characteristics,efficacy and outcome of 168 patients with PDAP treated in our hospital were retrospectively analyzed.Results:The main factor related to PDAP was operational pollution.Among the 168 patients with PDAP,132 patients showed positive results in microbial culture,including 78 cases(59.09%)infected by gram-positive bacteria,31cases(23.48%)by gram-negative bacteria,14 cases(10.6%)by fungi and 9 cases(6.82%)by mixed infections.Conclusion:The incidence of PDAP is closely related to non-standard operation and malnutrition.Grampositive bacteria are still the main pathogens and the withdrawal rate of patients with fungal infection is high.

关 键 词：腹膜透析 腹膜炎 致病菌 耐药性 

分 类 号：R459.5[医药卫生—治疗学]