造血干细胞移植患者红细胞输血效果的影响因素分析  

Analysis of Influence Factors of Erythrocyte Transfusion in Patients with Hematopoietic Stem Cell Transplantation

作　　者：马春娅[1] 孙晓琳[1] 封彦楠 张晓娟[1] 姜旭[1] 于洋[1] 汪德清[1] MA Chun-ya;SUN Xiao-lin;FENG yan-nan(Department of Blood Transfusion,The PLA General Hospital,Beijing 100853)

机构地区：[1]解放军总医院输血科

出　　处：《临床输血与检验》2019年第4期341-344,共4页Journal of Clinical Transfusion and Laboratory Medicine

基　　金：解放军总医院医疗大数据研发项目（No.2016MBD-023）资助

摘　　要：目的分析造血干细胞移植患者红细胞输血效果的影响因素,提高输血效果。方法通过临床输血管理系统,回顾性分析2016年1~12月造血干细胞移植患者输血前后基本信息及血液信息,以红细胞输注前后血红蛋白变化为因变量,其他调查指标为自变量,应用多因素线性回归模型,计算红细胞输血效果的影响因素。结果89例造血干细胞移植患者,共输注红细胞409次,影响红细胞输血效果的因素包括患者输血前脉搏、身高、体重、单次红细胞输血量、红细胞保存天数。结论造血干细胞移植患者应尽量选择保存天数较短的红细胞输注,对处于血型转型期的患者,应根据具体血清学格局制定个体化的输血策略输注红细胞。Objective To analyze the influencing factors of red blood cell transfusion in patients with hematopoietic stem cell transplantation so as to improve the efficacy of blood transfusion.Methods The fundamental information before and after transfusion in patients who had underwent hematopoietic stem cell transplantation were retrospectively analyzed from January 2016 to December 2016.The changes in hemoglobin were used as the dependent variables whereas other indicators,as independent variables.The model of multi-factor linear regression analysis was used to calculate the influencing factors of transfusion.Results A total of 409 person-times of transfusions were performed in 89 patients with hematopoietic stem cell transplantation.The heart rate,height,weight,volume of single transfusion,and days of blood preservation were considered as influencing factors.Conclusion Patients with hematopoietic stem cell transplantation benefit from the blood with fresh preservation.For patients in the blood group transition stage,individual strategy should include the blood according to specific serological patterns.

关 键 词：造血干细胞移植 红细胞输血 输血效果 ABO血型 

分 类 号：R457.1[医药卫生—治疗学]