大蒜素胶囊联合柳氮磺吡啶治疗溃疡性直肠炎  

Treatment of Ulcerative Proctitis With Allicin Capsule Combined With Sulfasalazine

作　　者：张红[1] ZHANG Hong(Department of Gastroenterology,Tengzhou Hospital of Traditional Chinese Medicine,Tengzhou Shandong 277500,China)

机构地区：[1]山东省滕州市中医医院消化内科

出　　处：《中国继续医学教育》2019年第22期106-108,共3页China Continuing Medical Education

摘　　要：目的探讨观察大蒜素胶囊联合柳氮磺吡啶治疗溃疡性直肠炎的临床效果。方法选择2017年2月-2018年9月内收诊的142例溃疡性直肠炎患者并将其分成两组,对照组行柳氮磺吡啶治疗,治疗组行柳氮磺吡啶+大蒜素胶囊治疗,观察比较两组患者的临床疗效,同时,经随访统计复发情况。结果(1)治疗组总有效率高于对照组(95.77%vs 84.51%),差异有统计学意义(P<0.05);(2)治疗组复发率低于对照组(5.63%vs 16.91%),组间数据比较,差异有统计学意义(P<0.05)。结论大蒜素胶囊+柳氮磺吡啶治疗溃疡性直肠炎,疗效显著,而且复发率低。Objective To discuss and observe the clinical efect of allicin capsule combined with sulfasalazine in the treatment of ulcerative proctitis.Methods 142 patients with ulcerative proctitis admitted to the hospitalfrom February 2017 to September 2018 were selected and divided into twogroups, the control group was given sulfasalazine treatment, the treatmentgroup was given sulfasalazine + allicin capsule treatment. The clinicalefcacy of the two groups was observed and compared. At the same time,the recurrence situation was statistically analyzed by follow-up. Results(1)The total effective rate of the treatment group was higher than that ofthe control group (95.77% vs 84.51%), the difference was statisticallysignifcant (P < 0.05). The recurrence rate of the treatment group was lowerthan that of the control group (5.63% vs 16.91%). There was statisticallysignificant difference between the two groups (P < 0.05). ConclusionAllicin capsule plus sulfasalazine is efective in the treatment of ulcerativeproctitis, and the recurrence rate is low.

关 键 词：大蒜素胶囊 柳氮磺吡啶 溃疡性直肠炎 临床疗效 复发率 联合用药 

分 类 号：R944[医药卫生—药剂学]