三个C19-二萜生物碱的NMR数据全归属（英文）  

Complete Assignments of NMR Spectral Data of Three C19-Diterpenoid Alkaloids

作　　者：尹田鹏 王雅溶 王敏 石文智 张正茜 何莎莎 YIN Tian-peng;WANG Ya-rong;WANG Min;SHI Wen-zhi;ZHANG Zheng-qian;HE Sha-sha(Zhuhai Key Laboratory of Fundamental and Applied Research in Traditional Chinese Medicine,Zunyi Medical University Zhuhai Campus,Zhuhai 519041,China)

机构地区：[1]遵义医科大学珠海校区珠海市中药基础及应用研究重点实验室

出　　处：《波谱学杂志》2019年第3期331-340,共10页Chinese Journal of Magnetic Resonance

基　　金：the National Natural Science Foundation of China(31860095);Guizhou Science and Technology Foundation of China(QKHJC[2018]1193);Zhuhai Premier-Discipline Enhancement Scheme of Pharmacology,Zhuhai Campus of Zunyi Medical University

摘　　要：C19-二萜生物碱结构复杂多样,核磁共振(NMR)结构鉴定困难.本文从独龙乌头中分离得到三个C19-二萜生物碱:taronenine E(1)、chasmaconitine(2)和vilmorisine(3),综合运用多种NMR技术(包括1H NMR、13C NMR、DEPT、1H-1H COSY、HSQC和HMBC),对其NMR数据进行了完整归属和部分修正,为该类化合物的深入研究提供了参考.C19-diterpenoid alkaloids have complex and diverse structures,posing great challenges for nuclear magnetic resonance(NMR)-based structural elucidation.Three C19-diterpenoid alkaloids,including taronenine E(1),chasmaconitine(2)and vilmorisine(3),were isolated from the roots of Aconitum taronense Fletcher et Lauener,and analyzed by various NMR spectroscopy methods(i.e.,1H and 13C NMR,DEPT,1H-1H COSY,HSQC and HMBC).Complete assignments of the NMR chemical shifts were obtained,providing a good reference for the further research of C19-diterpenoid alkaloids.

关 键 词：C19-二萜生物碱 独龙乌头(Aconitum taronense FLETCHER ET Lauener) 核磁共振(NMR) 归属 

分 类 号：O482.53[理学—固体物理]