踝臂血压指数与冠心病病变严重程度的相关性分析  

Ankle brachial index and the severity of coronary heart disease: a correlative study

作　　者：唐云月 崔雅琴 蒋建萍[3] TANG Yun-yue;CUI Ya-qin;JIANG Jian-ping(Department of Urology,the People’s Hospital of Anji,Huzhou 313300;Hyperbaric Oxygen Chamber,the People’s Hospital of Anji,Huzhou 313300;Internal Medicine-Cardiovascular Department,the First People’s Hospital of Huzhou,Huzhou 313300,China)

机构地区：[1]安吉县人民医院泌尿外科,浙江湖州313300 [2]安吉县人民医院高压氧室,浙江湖州313300 [3]湖州市第一人民医院心内科,浙江湖州313300

出　　处：《健康研究》2019年第4期381-384,共4页Health Research

基　　金：浙江省医药卫生科技计划项目(2018ZH042)

摘　　要：目的探讨踝臂血压指数(ankle brachial index,ABI)与冠心病病变严重程度的相关性,寻找评估冠心病病变严重程度的无创检测方法。方法根据选择性冠状动脉造影(coronary angiography,CAG)检查结果的192例患者,分为冠脉血管正常组(42例)、单支病变组(50例)、双支病变组(50例)和严重病变组(50例);采用Gensini积分法量化评估所有入选者的冠状动脉病变严重程度,测定入选者的ABI。比较4组患者的Gensini积分和ABI,并作Person相关性分析。结果冠脉血管正常组、单支病变组、双支病变组和严重病变组的Gensini积分依次增高且ABI依次下降,差异具有统计学意义(P<0.05);ABI与Gensini积分呈负相关(r=-0.652,P=0.023)。结论ABI是对于筛选和诊断冠心病具有极强辅助作用的无创检测指标,对冠心病患者的病变严重程度具有预测价值。Objective To determine the possible correlation of ankle brachial index(ABI)and the severity of coronary heart disease so as to find a non-invasive method for assessing the severity of coronary heart disease.Methods Firstly,according to the results of selective coronary angiography(CAG),192 patients were divided into two groups,namely,group A(n=42,consisting of subjects with normal coronary artery),group B(n=50,consisting of subjects with single-vessel disease),group C(n=50,consisting of subjects with double-vessel disease),and group D(n=50,consisting of subjects with severe lesion).Next,the severity of the disease of the subjects in all groups was graded by using the Gensini integration method and then the ABI of all subjects were measured.Lastly,the Gensini scores and ABI of the groups were compared and subjected to Person analysis for the establishment of possible correlation between the ABI and Gensini scores.Results The Gensini scores of group A,group B,group C and group D were found to increase one more than the other incrementally while the ABI of the four groups decreased incrementally.The differences were statistically significant(P<0.05).ABI was negatively correlated with Gensini score(r=-0.652,P=0.023).Conclusions ABI can serve as a non-invasive detection index for the screening and diagnosis of coronary heart disease,which can help to predict the severity of coronary heart disease.

关 键 词：踝臂血压指数 冠心病 相关性 病变严重程度 

分 类 号：R541.4[医药卫生—心血管疾病]