乙草胺对大鼠肝细胞G蛋白偶联受体介导的胞浆钙离子振荡的调控  

Regulation of acetochlor on the G-protein-coupled receptors mediated calcium oscillation in rat hepatocytes

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作  者:张彬彬 王玖 ZHANG Bin-bin;WANG Jiu(School of Pharmacy,Binzhou Medical University,Yantai 264003,Shandong,China;School of Public Health and Management,Binzhou Medical University,Yantai 264003,Shandong,China)

机构地区:[1]滨州医学院药学院,山东烟台264003 [2]滨州医学院公共卫生与管理学院,山东烟台264003

出  处:《湖北农业科学》2019年第16期104-106,共3页Hubei Agricultural Sciences

摘  要:以大鼠肝细胞为研究对象,研究乙草胺对大鼠肝细胞G蛋白偶联受体介导胞浆钙振荡的调控。结果表明,单独乙草胺刺激不引发胞浆钙离子振荡,乙草胺和PE同时作用对肾上腺素能受体有抑制作用且具有明显的量效反应关系。The effects of different concentrations of acetochlor on the regulation of cytosolic calcium oscillation induced by G protein-coupled receptors in rat hepatocytes was investigated.The results showed that acetochlor and PE could inhibit PE receptors which the effect of acetochlor on it were dose-dependent,and acetochlor alone had no effect on PE receptors.

关 键 词:乙草胺 肾上腺素能受体 钙振荡 肝细胞 

分 类 号:Q2[生物学—细胞生物学] S482[农业科学—农药学]

 

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