牛羊精子体外获能最新研究进展  

Research Progress of in vitro Capacitation of Bovine and Ovine Sperm

作　　者：苏广华 杨磊 李光鹏 SU Guang-hua;YANG Lei;LI Guang-peng(The State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock,Inner Mongolia University,Hohhot 010070,China)

机构地区：[1]内蒙古大学省部共建草原家畜生殖调控与繁育国家重点实验室

出　　处：《内蒙古大学学报（自然科学版）》2019年第4期414-420,共7页Journal of Inner Mongolia University：Natural Science Edition

基　　金：高产优质转基因肉牛新品种培育(2016ZX08007-002)资助项目

摘　　要：获能是精子获得与卵母细胞识别、融合与实现受精的前提条件.在获能期间,精子发生了包括质膜通透性与流动性变化、膜内外离子动态变化、蛋白酪氨酸磷酸化与多级信号传导等极为复杂的生理生化反应.虽然已经成功获得多种体外受精动物,但体外受精胚胎的质量与效率远未达到预期.精子的体外获能是关键技术环节.本文仅就牛和羊精子体外获能研究相关最新进展进行介绍.Capacitation is a pre-requirement for recognition,fusion and fertilization between sperm and oocytes.Exclusive physiological and biochemical changes including permeability and fluidity of sperm membrane,ions changes across membrane,protein tyrosine phosphorylation and multiple signal transduction happen during sperm capacitation.Lots of in vitro fertilized(IVF)animals have already been produced.However,the efficiency and the quality of the IVF embryos are far from expectation.The in vitro capacitation of spermatozoa may be one of the most important influencing factors.The present review focused on the latest progresses of the invitrocapacitation research of bovine and ovine sperm.

关 键 词：膜脂 超激活 体外受精 胚胎 

分 类 号：S814.4[农业科学—畜牧学] Q78[农业科学—畜牧兽医]