Recent advances of allenes in the first-row transition metals catalyzed C-H activation reactions  

作　　者：Xiang-Lei Han Peng-Peng Lin Qingjiang Li 

机构地区：[1]School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510006,China [2]State Key Laboratory of Natural and Biomimetic Drugs,Peking University,Beijing 100191,China

出　　处：《Chinese Chemical Letters》2019年第8期1495-1502,共8页中国化学快报（英文版）

基　　金：support of this work by the National Natural Science Foundation of China (No. 21502242);the State Key Laboratory of Natural and Biomimetic Drugs (No. K20150215)

摘　　要：Transition-metal-catalyzed C–H activation reaction has proven to be a powerful and efficient tool for the formation of diverse C-C and C–X bond and construction of functional complex molecules.From the viewpoint of sustainable chemistry,the first-row transition metals,such as Mn,Fe,Co,Ni and Cu,have been recognized as cheap,environmentally friendly and reactively effective catalysts for a number of C-H functionalization reactions.However,compared with the commonly used alkenes and alkynes in the first-row transition-metal-catalyzed C–H activations,considerable achievements have just been made by the use of structurally unique and reactively rich allenes as coupling partners in recent years.This review summarizes the recent progress of the first-row transition-metal-catalyzed C–H activations with allenes.Transition-metal-catalyzed C–H activation reaction has proven to be a powerful and efficient tool for the formation of diverse C-C and C–X bond and construction of functional complex molecules. From the viewpoint of sustainable chemistry, the first-row transition metals, such as Mn, Fe, Co, Ni and Cu, have been recognized as cheap, environmentally friendly and reactively effective catalysts for a number of C-H functionalization reactions. However, compared with the commonly used alkenes and alkynes in the first-row transition-metal-catalyzed C–H activations, considerable achievements have just been made by the use of structurally unique and reactively rich allenes as coupling partners in recent years.This review summarizes the recent progress of the first-row transition-metal-catalyzed C–H activations with allenes.

关 键 词：ALLENE C-H FUNCTIONALIZATION First-row transition metal ANNULATION Regioselectivity 

分 类 号：O62[理学—有机化学]