SCNN1B and CA12 play vital roles in occurrence of congenital bilateral absence of vas deferens(CBAVD)  

作　　者：Ying Shen Huan-Xun Yue Fu-Ping Li Feng-Yun Hu Xiao-Liang Li Qian Wan Wen-Rui Zhao Ji-Gang Jing Di-Ming Cai Xiao-Hui Jiang 

机构地区：[1]Human Sperm Bank,West China Second University Hospital,Sichuan University,Chengdu 610041,China [2]Key Laboratory of Obstetric,Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education,West China Second University Hospital,Sichuan University,Chengdu 610041,China [3]Auckland University,Auckland 1142,New Zealand [4]Chengdu Neo-Life Hope Medical Testing Inc,Chengdu 61CX341,China [5]Ultrasound Diagnosis Department,West China Hospital,Sichuan University,Chengdu 610041,China

出　　处：《Asian Journal of Andrology》2019年第5期525-527,共3页亚洲男性学杂志（英文版）

摘　　要：Dear Editor,Congenital bilateral absence of the vas deferens(CBAVD),a complete or partial defect of the Wolffian duct derivatives,is found in>25% of men with obstructive azoospermia(OA),but the underlying pathological mechanism remains poorly understood.Previous research has shown that the most common disease associated with CBAVD is cystic fibrosis(CF),the predominant manifestations of which include progressive lung disease,pancreatic dysfunction,elevated sweat chloride electrolyte,meconium ileus,and male infertility.

关 键 词：ELEVATED CBAVD lung 

分 类 号：R69[医药卫生—泌尿科学]