具有较大Stokes位移的新型苯并噻二唑基pH荧光探针的制备及性能研究  

A benzothiadiazole-based fluorescent pH probe with large Stokes shift

作　　者：李阳 张辉 李明 Li Yang Zhang;Hui Li Ming(School of Chemistry and Life Science,Changchun University of Technology,Changchun 130012)

机构地区：[1]长春工业大学化学与生命科学学院

出　　处：《化工新型材料》2019年第8期135-139,共5页New Chemical Materials

基　　金：国家自然科学基金项目(21644003,21704006);吉林省教育厅“十三五”科学技术研究项目(吉教科合字[2016]第325号)

摘　　要：合成了2种基于苯并噻二唑的荧光探针C1和C2,应用于极酸性条件下pH检测。利用核磁共振氢谱仪、紫外-可见分光光度计、荧光分光光度计等对合成的荧光探针分子结构及其性能进行表征。结果表明:2种荧光探针均具有较大的斯洛克斯(Stokes)位移(>100nm),且C2具有优良的专一性和光稳定性;pH从0增加到3.04时,随着pH的升高,C2的荧光强度逐渐降低;C2探针的酸度系数为1.56,在极酸性条件下C2作为pH探针具有潜在的应用前景。Benzothiadiazole-based fluorescent probe molecules(C1 and C2)were synthesized for pH detection under extremely acidic conditions through a simple synthesis method.The probe molecular structure was characterized by 1H-NMR.UV-Vis spectra and fluorescence spectra were used to detect its properties.The results showed that both molecules had a large Stokes shift(>100nm),and C2 had excellent specificity and light stability under strong acid condition.The titration results showed that the fluorescence intensity gradually decreased with increasing pH from 0 to 3.04.The pKa of the C2 probe was 1.56.The results indicated that C2 molecules had potential application as pH probes under extremely acidic conditions.

关 键 词：苯并噻二唑 Stokes位移 极酸性条件 PH敏感 

分 类 号：O65[理学—分析化学]