烟雾病的研究进展  

Progress in research on moyamoya disease

作　　者：胡淼 余金[1] 苏康 易雷 陈科宇 马志阳 蔡远坤 陈劲草[1] 章剑剑 HU Miao;YU Jin;SU Kang;YI Lei;CHEN Keyu;MA Zhiyang;CAI Yuankun;CHEN Jincao;ZHANG Jianjian(Zhongnan Hospital of Wuhan University,Wuhan 430000,China)

机构地区：[1]武汉大学中南医院

出　　处：《中国实用神经疾病杂志》2019年第15期1736-1740,共5页Chinese Journal of Practical Nervous Diseases

基　　金：国家自然科学基金(编号:81671157)

摘　　要：烟雾病(moyamoya disease)是一种罕见的脑血管疾病,其特征是颈内动脉末端及其主要分支逐渐狭窄、闭塞,并导致在颅底部形成代偿微血管网络。该血管网在血管造影上的外观看起来就像一股烟雾在空中飘过,因此,在1969年,铃木和TAKAKU将这种新型疾病称为“烟雾病”。现在已知烟雾病病理学的主要特征是颈内动脉终末的进行性狭窄,且烟雾血管是扩张的穿支动脉,起到侧支通路的作用。本文就烟雾病的发病机制、流行病学、临床特征及诊断等作一综述。Moyamoya disease,also known as Moyamoya disease or abnormal vascular network of the brain,is narrowed or occluded due to the thickening of the intracranial initial segment of the internal carotid artery(ICA)and the middle cerebral artery(MCA)or anterior cerebral artery(ACA).Thus,an abnormal vascular network appears at the bottom of the brain,which is named after the cerebral angiography in the form of cerebral angiography.There are significant regional differences in the pathogenesis of moyamoya disease,and the etiology mechanism is still not very clearly.The content of the related aspects of the pathogenesis and epidemiology of moyamoya disease is as follows.

关 键 词：烟雾病 脑血管疾病 发病机制 流行病学 临床特征 

分 类 号：R651[医药卫生—外科学]