上海松江地区性传播疾病病原体感染特点分析  

Analysis of the characteristics of sexually transmitted disease infection in Songjiang District of Shanghai

作　　者：曹辉[1] 夏万宝 丁夏丽 刘军[1] 彭敬红[1] CAO Hui;XIA Wanbao;DING Xiali;LIU Jun;PENG Jinghong(Department of Clinical Laboratory,Shanghai Songjiang Central Hospital,Shanghai 201600,China)

机构地区：[1]上海市松江区中心医院检验科

出　　处：《检验医学》2019年第9期804-807,共4页Laboratory Medicine

摘　　要：目的分析上海市松江区沙眼衣原体(CT)、淋病奈瑟菌(NG)、解脲脲原体(UU)感染及耐药情况,为性传播疾病的防治提供依据。方法收集15 768例患者CT、NG、UU的检测数据并进行统计分析。结果CT、NG和UU的阳性检出率分别为5.07%、8.62%和41.48%。不同年龄组CT感染无明显差异(P=0.107 5);≥51岁组NG阳性率最高(19.19%)(P<0.000 1);41~50岁组UU阳性检出率最高(48.97%)(P<0.000 1)。女性患者CT及UU阳性检出率均明显高于男性患者(P<0.000 1),男性患者NG阳性检出率明显高于女性患者(P<0.000 1)。UU对交沙霉素、米诺环素、强力霉素及氧氟沙星敏感性较高,分别为98.64%、97.83%、97.58%、81.92%。结论上海松江地区性传播疾病患者UU感染率最高,抗感染治疗应以高敏感性的抗菌药物为主。Objective To analyze the infection and drug resistance of Chlamydia trachomatis(CT),Neisseria gonorrhoeae(NG)and Ureaplasma urealyticum(UU)in Songjiang District of Shanghai,and to provide a reference for the prevention and treatment of sexually transmitted disease.Methods The data of CT,NG and UU determinations from 15 768 patients were collected and analyzed statistically.Results The positive determination rates of CT,NG and UU were 5.07%,8.62%and 41.48%,respectively.There was no statistical significance in CT infection between different age groups(P=0.107 5).The NG positive determination rate was the highest in patients with≥51 years old(19.19%,P<0.000 1),and the UU positive determination rate was the highest in patients with 41-50 years old(48.97%,P<0.000 1).The positive determination rates of CT and UU in female patients were higher than those in male patients(P<0.000 1).The NG positive determination rate in male patients was higher than that in female patients(P<0.000 1).The drug susceptibility test for UU showed that the antibiotics with higher drug susceptibility were josamycin(98.64%),minocycline(97.83%),doxycycline(97.58%)and ofloxacin(81.92%).Conclusions In Songjiang District of Shanghai,UU has the highest infection rate.The treatment of UU infection should be based on antibiotics with high drug susceptibility.

关 键 词：沙眼衣原体 淋病奈瑟菌 解脲脲原体 上海 松江地区 

分 类 号：R446.1[医药卫生—诊断学]