胺碘酮治疗41例急性心肌梗死室性心律失常的临床疗效  

Clinical efficacy of amiodarone in the treatment of 41 patients with acute myocardial infarction ventricular arrhythmia

作　　者：叶贞发 赖心味 叶齐饶 陈丰[2] Ye Zhenfa;Lai Xinwei;Ye Qirao;Chen Feng(Department of Internal Medicine,Shanghao County People's Hospital,Ganzhou,Jiangxi,341200,China;Department of Cardiology,Ganzhou People's Hospital,Ganzhou,Jiangxi,341000,China)

机构地区：[1]江西省上犹县人民医院内一科,江西赣州341200 [2]江西省赣州市人民医院心内科,江西赣州341000

出　　处：《当代医学》2019年第28期56-58,共3页Contemporary Medicine

基　　金：江西省赣州市指导性科技计划项目(GZ2018ZSF4)

摘　　要：目的探讨41例急性心肌梗死室性心律失常患者应用胺碘酮进行治疗的临床效果。方法选取2015年10月至2018年10月就诊于本院并接受相应治疗的众多急性心肌梗死室性心律失常患者中随机选择82例作为本次研究对象,并同时依照临床治疗方案的不同将其分为两组(参照组与实验组)进行差异性治疗。其中,采用利多卡因对参照组患者进行常规性治疗,实验组患者则在前者的基础上联合胺碘酮进行综合性治疗,对两组患者的临床疗效、不良反应发生率以及治疗期间的发病次数与接受治疗前后的心功能指标变化情况进行对比分析。结果实施针对性治疗方案后,实验组患者治疗期间发病次数等临床指标均优于参照组,差异具有统计学意义(P<0.05)。其中,实验组患者的临床治疗总有效率为97.56%,治疗期间的平均发病次数为(122.10±54.25)次,参照组患者的临床治疗总有效率为78.05%,治疗期间的平均发病次数为(323.45±54.23)次。结论在采用利多卡因对急性心肌梗死室性心律失常患者行常规性治疗方案的同时辅以胺碘酮对其进行联合治疗,有利于在优化其心功能指标的基础上减少治疗期间的发病次数,从而进一步改善临床治疗效果和有效降低心动过缓等不良反应的发生率,值得临床大力借鉴与推广。Objective To investigate the clinical effect of amiodarone in 41 patients with acute myocardial infarction ventricular arrhythmia.Methods A total of 82 patients with acute myocardial infarction ventricular arrhythmia who were treated in our hospital from October 2015 to October 2018 were randomly selected as the study subjects,and they were also treated according to different clinical treatment plans.Divided into two groups(reference group and experimental group)for differential treatment.Among them,lidocaine was used for routine treatment of patients in the reference group,and patients in the experimental group were treated with amiodarone on the basis of the former.The clinical efficacy,incidence of adverse reactions and incidence during treatment were compared between the two groups.The number of times was compared with the changes in cardiac function indicators before and after treatment.Results After the targeted treatment program was implemented,Clinical indicators such as the number of incidence of patients in the experimental group during treatment were better than those in the reference group,with statistically significant differences(P<0.05).Among them,the total effective rate of clinical treatment in the experimental group was 97.56%,and the average number of cases during the treatment period was(122.10±54.25)times.The total effective rate of clinical treatment in the reference group was 78.05%,and the average number of cases during the treatment period was(323.45±54.23)times.Conclusion The use of lidocaine for routine treatment of patients with acute myocardial infarction ventricular arrhythmia combined with amiodarone for combination therapy is beneficial to reduce the number of episodes during treatment based on optimization of cardiac function indicators.In order to further improve the clinical treatment effect and effectively reduce the incidence of adverse reactions such as bradycardia,it is worthy of clinical reference and promotion.

关 键 词：胺碘酮 急性心肌梗死室性心律失常 不良反应发生率 心功能指标 

分 类 号：R54[医药卫生—心血管疾病]