登革热病程影响因素及临床特征分析  

Analysis of influencing factors and clinical characteristics of dengue fever course

作　　者：周钿 洪英极 孙铭繁 林宇行 林东峰 林昆 ZHOU Tian;HONG Yingji;SUN Mingfan;LIN Yuxing;LIN Dongfeng;LIN Kun(Department of Preventive and Health Care,Chaozhou People’s Hospital,Chaozhou 521000,China;Department of Public Health and Preventive Medicine,Shantou University Medical College,Shantou 515041,China)

机构地区：[1]潮州市人民医院预防保健科,广东潮州521000 [2]汕头大学医学院公共卫生与预防医学教研室,广东汕头515041

出　　处：《汕头大学医学院学报》2019年第3期154-156,共3页Journal of Shantou University Medical College

摘　　要：目的:探讨影响登革热病程的因素及临床特征,为登革热的诊治提供参考依据。方法:回顾性分析2015年某市766例登革热患者的病例资料,对患者临床特征进行描述性统计分析;采用多元逐步回归模型探讨登革热病程的影响因素。结果:登革热患者主要临床表现为发热(100%)和肌肉关节疼痛(79.63%)。实验室检查多数患者表现为血清钠降低(67.36%)、门冬氨酸氨基转移酶升高(57.44%)。血小板计数可能是登革热病程的主要影响因素(R^2=0.093)。结论:登革热患者临床症状明显,通过提高血小板计数及血钠水平缩短病程值得进一步研究。Objective:To investigate the factors influencing the course and clinical characteristics of dengue fever,and to provide reference for the diagnosis and treatment of dengue fever.Methods:The data of 766 cases of dengue fever in a city in 2015 were retrospectively analyzed.The clinical characteristics of the patients were analyzed by descriptive statistical analysis.The influencing factors of the course of dengue fever were discussed by multiple stepwise regression model.Results:The main clinical manifestations of dengue fever were fever(100%)and muscle and joint pain(79.63%).Laboratory examination showed that most patients had lower serum sodium(67.36%)and higher aspartate aminotransferase(57.44%).Platelet count may be a major factor in the course of dengue fever(R2=0.093).Conclusion:The clinical symptoms of patients with dengue fever are obvious.It is worth further study to shorten the course of disease by increasing platelet count and serum sodium level.

关 键 词：登革热 病程 临床特征 临床流行病学 

分 类 号：R512.8[医药卫生—内科学]