妊娠糖尿病IADPSG新诊断标准与母婴结局分析  

Analysis of IADPSG new diagnostic criteria for gestational diabetes mellitus and maternal and infant outcomes

作　　者：王红红[1] 骆硕 董巍巍 郭婧 赵霞[1] 王玉娇 李克用 WANG Honghong;LUO Shuo;DONG Wewei;GUO Jing;ZHAO Xia;WANG Yujiao;LI Keyong(Department of Gynaecology and Obstetrics,Baoding Maternal and Child Health Hospital,Baoding,Hebei 071000,China)

机构地区：[1]保定市妇幼保健院妇产科

出　　处：《国际检验医学杂志》2019年第18期2205-2208,共4页International Journal of Laboratory Medicine

基　　金：保定市科技计划项目(18ZF162)

摘　　要：目的探讨2010年国际妊娠合并糖尿病研究组织(IADPSG)推荐的妊娠期糖尿病(GDM)诊断新标准对母儿结局的影响。方法选取2015年1月至2017年12月在该院产检及分娩的孕妇1 586例作为研究对象,应用IADPSG标准诊断为GDM的238例作为新标准GDM组,剩余的1 348例作为对照组;应用1979年美国国家糖尿病数据组(NDDG)标准诊断为GDM的86例孕妇为旧标准GDM组;新标准组中相较于旧标准组新增的GDM孕妇作为新增GDM组。记录并比较各组孕妇的一般资料、诊治情况及母婴结局。结果新标准GDM组的平均年龄、孕前体质量指数(BMI)、血红蛋白及血糖水平明显高于对照组,新标准GDM组、旧标准GDM组的妊高征发病率、早产儿和巨大儿率明显高于对照组,差异有统计学意义(P<0.05);新增GDM组的妊高征发病率、早产儿和巨大儿率明显高于对照组,差异有统计学意义(P>0.05)。结论IADPSG推荐的GDM诊断新标准可使更多的GDM孕妇纳入管理,有利于早期通过科学、合理的措施进行干预,降低各种母婴并发症的发生,改善母婴结局。Objective To investigate the impact of the new diagnostic criteria for gestational diabetes mellitus(GDM)recommended by the International Association of Diabetic Pregnancy Study Group(IADPSG)in 2010 on maternal and fetal outcomes.Methods A total of 1 586 pregnant women who underwent antepartum examination and delivered in our hospital from January 2015 to December 2017 were enrolled in the study.Among those people,238 pregnant women diagnosed as GDM by using IADPSG standard were selected as the new standard GDM group,and the remaining 1 348 cases as the control group.Meanwhile 86 cases diagnosed as GDM using the National Diabetes Data Group(NDDG)standard of 1979 were selected as the old standard GDM group;compared with the old standard GDM group,the increased pregnant women diagnosed with GDM in the new standard GDM group were selected as the increased GDM group.The general condition,diagnosis and treatment,and maternal and infant outcomes of pregnant women in each group were recorded and compared among the groups.Results The average age,pre-pregnancy BMI,hemoglobin and blood glucose levels of the new standard GDM group were significantly higher than those of the control group,and the incidence of PIH,premature delivery and macrosomia in the new standard GDM group and the old standard GDM group were significantly higher than those of the control group(P<0.05).The rates of premature delivery and macrosomia in the increased GDM group were significantly higher than those of the control group(P>0.05).Conclusion The new diagnostic criteria for GDM recommended by IADPSG allows more GDM women to be included in the GDM management,which is conducive to early intervention through scientific and rational measures in order to reduce the incidence of various maternal and child complications and improve maternal and infant outcomes.

关 键 词：妊娠糖尿病 新诊断标准 母婴结局 

分 类 号：R446.11[医药卫生—诊断学]