西双版纳州感染嗜肝病毒和结核杆菌登革热病例临床特征分析  

Clinical characteristics of dengue cases infected hepatotropic virus and Mycobacterium tuberculosis in Xishuangbanna prefecture

作　　者：崔新国 唐利彬 周红宁 姜进勇 黄民强 Cui Xinguo;Tang Libin;Zhou Hongning;Jiang Jinyong;Huang Minqiang(Yunnan Provincial Key Laboratory of Vector-borne Disease Control and Research,Yunnan Collaborative Innovation Center for Public Health and Disease Prevention and Control;The Nanxiang Hospital of Jiading District,Shanghai 201802,China)

机构地区：[1]云南省虫媒传染病防控研究重点实验室,云南省虫媒病毒研究中心,云南省公共卫生协同创新中心,大理大学病原与媒介生物研究所(普洱分部)云南省寄生虫病防治所,普洱665000 [2]上海市嘉定区南翔医院,201802

出　　处：《中华实验和临床病毒学杂志》2019年第4期424-427,共4页Chinese Journal of Experimental and Clinical Virology

基　　金：云南省重大科技专项(2017ZF007);国家自然科学基金(U1602223,81160357,30960327,30660160);中英学者基金资助项目(313669);金宁一院士工作站项目,云南公共卫生与疾病防控协同创新中心项目(2014YNPHXT03)。

摘　　要：目的探讨西双版纳州感染嗜肝病毒和结核杆菌登革热病例的临床特征,为医疗机构制定有效的合并感染其他疾病的登革热诊疗方案提供依据。方法对2013年和2015年西双版纳州感染嗜肝病毒和结核杆菌住院登革热病例进行病例症状、体征和相关生化指标回顾性分析。结果感染嗜肝病毒登革热病例临床特征典型,尿常规异常、凝血功能异常和高乳酸脱氢酶的发生率低;感染结核杆菌登革热病例休克、高红细胞比容、肾功能和凝血功能异常的发生率高,重症化倾向较明显。结论感染结核杆菌登革热病例发生重症几率较感染嗜肝病毒登革热病例高,提示医疗机构对感染结核杆菌登革热病例应采取及时救治,防止重症发生。Objective To study the clinical features of dengue cases infected with hepatotropic virus and Mycobacterium tuberculosis in Xishuangbanna,and to provide evidences to set up effective treatment programs for the dengue patients infected with the other diseases for hospitals.Methods The clinical characteristics of dengue cases infected hepatotropic virus and Mycobacterium tuberculosis were analyzed retrospectively on their symptoms and biochemical parameters from the People′s Hospital and the Infectious Disease Hospital of Xishuangbanna Prefecture in 2013 and 2015.Results The clinical characteristics of dengue cases infected with hepatotropic virus were typical,and inclued low incidence of urinary abnormalities,coagulation disorders and high-lactate dehydrogenase.Dengue cases infected with Mycobacterium tuberculosis had high incidence of shock,high-hematocrit,renal function and coagulation abnormalities,which suggested a trend of more serious illness than other groups obviously.Conclusions The rate of severe disease was higher in dengue cases infected with Mycobacterium tuberculosis than those infected with hepatotropic virus,which suggests that the dengue cases infected with Mycobacterium tuberculosis should be treated timely to reduce the severity of the diseases in the hospital.

关 键 词：登革热 嗜肝病毒 结核杆菌 临床特征 

分 类 号：R51[医药卫生—内科学]