慢性血栓栓塞性疾病的研究进展  

Research progress of chronic thromboembolic disease

作　　者：刘晔 许小毛[2] Liu Ye;Xu Xiaomao(The MOH Key Laboratory of Geriatrics,Beijing Hospital,National Center of Gerontology,Beijing 100730,China;Department of Respiratory and Critical Care Medicine,Beijing Hospital,National Center of Gerontology,Beijing 100730,China)

机构地区：[1]北京医院国家老年医学中心卫生部老年医学重点实验室,100730 [2]北京医院国家老年医学中心呼吸与危重症医学科,100730

出　　处：《国际呼吸杂志》2019年第17期1349-1352,共4页International Journal of Respiration

基　　金："十三五"国家精准医学研究课题(2016YFC0905602);"十二五"国家科技支撑计划(2011BAI11B17)。

摘　　要：若急性肺血栓栓塞后肺动脉内血栓未完全溶解,在肺动脉内遗留残余血栓并机化,可进一步发展至慢性血栓栓塞性疾病。其发病隐匿,影响患者预后。本文就近年来慢性血栓栓塞性疾病的病理生理、临床表现及诊断治疗等方面的研究进展进行综述,以期为临床治疗及研究、预防慢性血栓栓塞性肺动脉高压提供参考。If the thrombus in pulmonary artery is not completely dissolved after acute pulmonary thromboembolism,residual thrombus in the pulmonary artery can be further developed to chronic thromboembolic disease.The incidence is hidden,which affects the prognosis of patients.This article reviews the research progress of pathophysiology,clinical manifestations,diagnosis and treatment of chronic thromboembolic disease in recent years,in order to provide inspiration for clinical treatment and research and prevention of chronic thromboembolic pulmonary hypertension.

关 键 词：慢性血栓栓塞性疾病 慢性血栓栓塞性肺动脉高压 肺动脉内膜血栓剥脱术 球囊肺血管成形术 

分 类 号：R54[医药卫生—心血管疾病]