潍坊某高校教师甲状腺结节与焦虑抑郁状态相关性研究  

Prevalence of thyroid nodules and correlation with anxiety and depression among teachers from a university in Weifang city

作　　者：郎芳[1] 王唯平[1] 郑德伟[2] 李霞[3] 王艳霞[4] 张增国[5] LANG Fang;WANG Weiping;ZHENG Dewei;LI Xia;WANG Yanxia;ZHANG Zengguo(Physical Examination Department,the Affiliated Hospital of Weifang Medical University,Weifang 261031,China;Department of Psychology,Weifang Medical University;Department of Ophthalmology,the Affiliated Hospital of Weifang Medical University;Department of Stomatology,the Affiliated Hospital of Weifang Medical University;School of Public Health and Management,Weifang Medical University)

机构地区：[1]潍坊医学院附属医院体检科,山东潍坊261031 [2]潍坊医学院心理学系 [3]潍坊医学院附属医院眼科 [4]潍坊医学院附属医院口腔科 [5]潍坊医学院公共卫生与管理学院

出　　处：《潍坊医学院学报》2019年第4期259-262,共4页Acta Academiae Medicinae Weifang

基　　金：山东省医药卫生科技发展计划项目(项目编号:2017WSB28009);潍坊市软科学研究计划项目(项目编号:2017RKX138);潍坊医学院博士基金启动项目(项目编号:2017BSQD56)

摘　　要：目的调查潍坊某高校教师甲状腺结节的流行状况,探讨焦虑抑郁与甲状腺结节的相关性。方法采用一般情况调查问卷、甲状腺超声、焦虑自评量表(SDS)、抑郁自评量表(SAS)、体格检查等方法,收集2015年5月~2016年5月在本院健康体检的634例高校教师的临床资料,分析该人群甲状腺结节的流行状况及焦虑抑郁状态与甲状腺结节的相关性。结果甲状腺结节总检出率为27.29%(173/634),男性和女性检出率分别为18.97%(48/253)和32.81%(125/381),性别差异具有显著性(χ^2=14.669,P<0.01),甲状腺结节检出率随年龄增加而逐渐升高。甲状腺结节检出率与抑郁程度和焦虑程度均呈正相关(r=0.361,P<0.01;r=0.214,P<0.01);多因素logistic回归分析结果显示:女性(OR=2.28,P<0.01)、年龄≥40岁(OR=1.309,P<0.01)、经常食用海产品(OR=1.916,P<0.05)、超重及肥胖(OR=1.754,P<0.05)、糖尿病(OR=2.591,P<0.05)、焦虑(OR=1.537,P<0.05)、抑郁(OR=1.718,P<0.05)等是甲状腺结节发病的危险因素。结论甲状腺结节在人群中患病率较高,随年龄增长而增加。甲状腺结节发病与焦虑抑郁相关,改善生活方式、调整情绪、缓解生活和工作压力可能降低甲状腺结节的患病率。Objective To explore the prevalence of thyroid nodules and correlation with anxiety and depression among teachers from a university in Weifang city.Methods General data of 634 cases of health examination information in our hospital from May 2015 to May 2016 were collected through questionnaire,thyroid ultrasound examination,physical examination and other methods,and the prevalence of thyroid nodules and correlation with anxiety and depression were analyzed.Results Total detection rate of thyroid nodules was 27.29%(173/634) in examinees,the male’s detection rate was 18.97%(48/253) and the female’s detection rate was 32.81%(125/381),there was significant difference in gender(χ^2=14.669,P<0.01),and the detection rate increased with age.The incidence of thyroid nodules were positively correlated with the degree of depression and anxiety(r=0.361,P<0.01;r=0.214,P<0.01).Logistic regression showed that female(OR=2.28,P<0.01),age≥40 years old(OR=1.309,P<0.01),taking seafood frequently(OR=1.916,P<0.05),overweight and obesity(OR=1.754,P<0.05),diabetes(OR=2.591,P<0.05),anxiety(OR=1.537,P<0.05) and depression(OR=1.718,P<0.05) were risk factors of thyroid nodules.Conclusion The prevalence of thyroid nodules is high,increased with age and positively correlated with anxiety and depression.Incidence of thyroid nodules can be reduced by regulating the lifestyle,adjusting mood and alleviating stress.

关 键 词：甲状腺结节 焦虑 抑郁 危险因素 

分 类 号：R581[医药卫生—内分泌]