依达拉奉联合阿托伐他汀钙片治疗改善急性脑梗死患者的临床治疗效果  

Edaravone combined with atorvastatin calcium promote the clinical therapeutic effect of acute cerebral infarction

作　　者：梁明俊[1] 邓光荣 甄新焕[1] Liang Mingjun;Deng Guangrong;Zhen Xinhuan(Department of Emergency,Kaiping Central Hospital,Jiangmen 529300,China)

机构地区：[1]开平市中心医院急诊科

出　　处：《中华脑科疾病与康复杂志（电子版）》2019年第3期154-157,共4页Chinese Journal of Brain Diseases and Rehabilitation（Electronic Edition）

摘　　要：目的研究依达拉奉联合阿托伐他汀钙片对急性脑梗死(ACI)患者的临床治疗效果。方法选择开平市中心医院急诊科自2015年1月至2017年10月收治的97例ACI患者作为研究对象,并根据治疗方案的差别分为实验组和对照组,对照组患者使用常规治疗,实验组患者在常规性治疗方案的基础上增加依达拉奉联合阿托伐他汀治疗,比较2组患者早期治疗效果、并发症以及恢复期日常生活能力情况。结果实验组基本痊愈病例数量较比对照组多,无效病例数显现更少,治疗总有效率高,差异均具有统计学意义(P<0.05);实验组患者在肺部感染的发生率上明显低于对照组(P<0.05),而在深静脉感染、褥疮、泌尿系统感染、营养不良上无明显差别(P>0.05),但是发生率均低于对照组;并且患者在疾病恢复期第6、9、12个月时日常生活能力量表评分均显著更高(P<0.05)。结论依达拉奉联合阿托伐他汀钙片能够提高ACI的临床治疗效果。Objective To study the clinical effect of Edaravone combined with atorvastatin calcium tablets on acute cerebral infarction.Methods Ninety-seven patients with acute cerebral infarction admitted to Kaiping Central Hospital from January 2015 to October 2017 were selected as the study subjects.According to the difference of treatment schemes,they were divided into experimental group(using edaravone combined with atorvastatin calcium tablets)and control group(conventional treatment group).The early treatment effect,complications,and recovery ability of daily life of the two groups were compared.Results Compared with conventional treatment,Edaravone combined with atorvastatin significantly increased the number of basic cured cases(P<0.05),while the number of ineffective cases showed less(P<0.05),and the total effective rate was significantly higher(P<0.05).The incidence of pulmonary infection in patients was significantly lower than that in the conventional treatment group(P<0.05),while there was no significant difference in deep venous infection,bedsores,urinary tract infection and malnutrition(P>0.05),but the incidence was lower than that in the conventional treatment group.In addition,the ADL scores of patients at the 6th,9th and 12th month of convalescence were significantly higher(P<0.05).Conclusion Edaravone combined with atorvastatin calcium tablets can improve the clinical effect of acute cerebral infarction.

关 键 词：急性脑梗死 依达拉奉 阿托伐他汀 

分 类 号：R47[医药卫生—护理学]