重庆地区儿童CA-MRSA感染的危险因素研究  

Study on Risk Factors of Children’s CA-MRSA in Chongqing

作　　者：侯秋苹 HOU Qiu-ping(Department of Pediatrics,the 13th People's Hospital of Chongqing,Chongqing 400053,China)

机构地区：[1]重庆市第十三人民医院儿科

出　　处：《医学信息》2019年第19期134-135,共2页Journal of Medical Information

基　　金：重庆市第十三人民医院资助项目(编号:2018YNXM04)

摘　　要：目的研究重庆地区儿童社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)感染的高危因素,为临床预防儿童感染CA-MRSA提供参考。方法选取2017年10月~2019年4月我院及其线路医院收治的200例呼吸道感染患儿作为研究对象。采用专用运输痰杯或拭子采样呼吸道感染患儿痰液或扁桃体分泌物,发热患儿则需进行血培养,检测标本并调查CA-MRSA发生情况及其危险因素。结果200例呼吸道感染患儿中MRSA发生128例(64.00%),其中CA-MRSA发生55例,在MRSA中构成比为42.97%。单因素分析显示不同年龄、抗菌药物应用史、住院或就诊史的患儿CA-MRSA感染率比较,差异有统计学意义(P<0.05);多因素回归分析显示,年龄、抗菌药物应用史是CA-MRSA发生的独立高危因素。结论重庆地区儿童CA-MRSA好发于5岁以下儿童,患儿普遍存在抗菌药物应用史,临床需加强对儿童CA-MRSA感染的重视,降低CA-MRSA的发病率与患病率。Objective To study the high risk factors of community acquired-methicillin resistant Staphylococcus aureus(CA-MRSA)infection in children's in Chongqing,and provide reference for clinical prevention of CA-MRSA infection in children.Methods A total of 200 children with respiratory infection admitted to our hospital from October 2017 to April 2019 were selected as subjects.A special transport cup or swab is used to sample the respiratory tract infection of children's sputum or tonsil secretions.Children with fever need to undergo blood culture,test specimens and investigate the occurrence of CA-MRSA and its risk factors.Results Of the 200 children with respiratory infection,128(64.00%)had MRSA,of which 55 were CA-MRSA,and the ratio of MRSA was 42.97%.Univariate analysis showed that the rates of CA-MRSA infection among children of different ages,antibiotics application history,hospitalization or visit history were statistically significant(P<0.05).Multivariate regression analysis showed that age and antibacterial application history were Independent high risk factors for CA-MRSA.Conclusion CA-MRSA in children in Chongqing is prevalent in children under 5 years of age.The history of antibacterial use is widespread in children.It is necessary to strengthen the attention of children with CA-MRSA infection and reduce the incidence and prevalence of CA-MRSA.

关 键 词：重庆地区 儿童 社区获得性 耐甲氧西林金黄色葡萄球菌 呼吸道感染 危险因素 

分 类 号：R725.1[医药卫生—儿科]