无精子症患者睾丸体积与睾丸抽吸取精术穿刺结果的相关性分析  

Clinical analysis of testicular volume and TESA results in patients with azoospermia

作　　者：武学海[1] 杨慧林[1] 马英兰[1] 向玉[1] 李燕子[1] 李斌业[2] WU Xue-hai;YANG Hui-lin;MA Ying-lan(Reproductive Center,Qinghai Red Cross Hospital,Xining Qinghai 810000,China)

机构地区：[1]青海红十字医院生殖中心,青海西宁810000 [2]青海省人民医院生殖中心,青海西宁810000

出　　处：《临床和实验医学杂志》2019年第19期2109-2111,共3页Journal of Clinical and Experimental Medicine

基　　金：青海省卫计委医药卫生科技项目(编号:2016-wjqh-01)

摘　　要：目的探讨无精子症患者睾丸体积与睾丸抽吸取精术(TESA)穿刺结果的相关性,了解TESA获取精子与严重少弱精子症两者卵胞浆内单精子显微注射技术(ICSI)助孕患者的妊娠率的差异。方法回顾性收集129例于2016年8月至2018年9月就诊于青海省红十字医院及青海省人民医院生殖中心无精子症患者的一般资料、睾丸大小、治疗情况等。按睾丸体积大小分为A组15例(睾丸体积≤12 ml)、B组29例(睾丸体积=15 ml)和C组85例(睾丸体积≥20 ml)。对3组间找到精子的比例进行对比分析。对行ICSI助孕的患者,根据精子来源于TESA患者或严重少弱精子症的患者的不同分为TESA组(16例)和ICSI组(21例),对两组患者的妊娠率进行对比分析。结果在A、B、C 3组患者中,A组只有1例患者找到精子,占该组患者的7.14%;B组共有7例患者找到精子,占该组患者31.82%;C组共有39例患者找到精子,占该组患者的84.78%。C组患者中找到精子的比率最高,与A组和C组比较,差异具有统计学意义(P<0.01)。A组和B组比较,B组患者找到精子的比率较高,差异具有统计学意义(P<0.05)。ICSI组患者与TESA组患者的妊娠率比较差异无统计学意义(P>0.05),ICSI组、TESA组妊娠率分别为42.86%(9/21)、50.00%(8/16)。结论在无精子症患者中,睾丸体积≤12 ml者在行TESA时找到精子的比率很低,睾丸体积=15 ml者行TESA找到精子的比率较大,而睾丸体积≥20 ml者行TESA找到精子的比率很大。TESA时找到精子与严重少弱精子症患者行ICSI助孕时并不影响其妊娠率。Objective To investigate the correlation between testicular volume and(Testicular sperm aspiration)TESA puncture results in azoospermia and to understand the difference of pregnancy rate between TESA sperm acquisition and severe oligoasthenospermia with ICSI to assist pregnancy.Methods A retrospective study about general information,testicular volume,treatment and etc.was conducted on 129 azoospermia patients treated in Qinghai Red Cross Hospital and Reproductive Center of Qinghai provincial People's Hospital from August 2016 to September 2018.According to testicular volume,15 cases were divided into group A(testicular volume≤12 ml),29 cases were divided into group B(testicular volume=12 ml)and 85 cases were divided into group C(testicular volume≥20 ml).The percentage of spermatozoa found among the three groups was compared and analyzed statistically.According to the Patients with ICSI to assist pregnancy were divided into group TESA(16 cases)and group ICSI(21 cases)according to the different origin of sperm from TESA patients or severe oligoasthenospermia patients.The pregnancy rates of the two groups were compared and analyzed statistically.Results Among group A,B and C,only one patient in group A found sperm,accounting for 7.14%of the patients in this group.7 patients in group B found sperm,accounting for 31.82%of the patients in this group.39 patients in group C found sperm,accounting for 84.78%of the patients in this group.The proportion of sperm found in group C was the highest,and the difference was statistically significant compared with group A and group C(P<0.01).The group A is compared with group B,the proportion of sperm found in group B was higher,and the difference was statistically significant(P<0.05).The difference was no statistically significant in pregnancy rate between group ICSI and group TESA(P>0.05).Pregnancy rates of group ICSI and group TESA were 42.86%(9/21)and 50.00%(8/16)respectively.Conclusion In patients with azoospermia,the proportion of spermatozoa found was very low when testi

关 键 词：无精子症 睾丸体积 睾丸抽吸取精术 妊娠率 

分 类 号：R71[医药卫生—妇产科学]