家禽H7N9流感免疫效果监测与分析  

Monitoring and analysis of the immune effects of avian H7N9 influenza

作　　者：董宏伟 王彦华 薛双[1] DONG Hongwei;WANG Yanhua;XUE Shuang(Zhumadian Center for Animal Disease Control and Prevention,Zhumadian,Henan 463000,China;Henan Provincial Forage and Feed Station,Zhengzhou,Henan 450008,China)

机构地区：[1]驻马店市动物疫病预防控制中心,河南驻马店463000 [2]河南省饲草饲料站,河南郑州450008

出　　处：《现代牧业》2019年第3期11-13,共3页Modern Animal Husbandry

摘　　要：为评估家禽H7N9流感的免疫效果,随机抽取驻马店市24家规模养殖场和部分散养户的健康家禽血清样品908份,采用血凝抑制试验方法对H7N9流感抗体进行检测。结果表明,家禽接种重组禽流感病毒(H5+H7)二价灭活疫苗后,抗体滴度从免疫前的小于等于2log2上升到大于等于5 log2,最高可达到10 log2以上。说明家禽接种该疫苗后体内能很快产生较高滴度的H7N9流感抗体,该疫苗具有良好的免疫效果。In order to scientifically assess the immune effects of avian H7N9 influenza in Zhumadian city,908 serum samples were selected from healthy poultry on 24 large-scale farms and some decentralized households,including 272 pre-immunization serum samples and 636 post-immunization serum samples.The hemagglutination inhibition test was conducted to detect the antibodies to H7N9 influenza.It was shown that the antibody titration was less than or equal to 2 log2 for all poultry before immunity,and above 5 log2 with the highest reaching 10 log2 for 83.31%of poultry inoculated with recombinant avian influenza virus(H 5+H 7)divalent inactivated vaccine.High-titer H7N9 antibodies were rapidly produced in poultry after vaccination with recombinant avian influenza virus(H 5+H 7)divalent inactivated vaccine,showing that the recombinant avian influenza virus(H 5+H 7)divalent inactivated vaccine could produce good immunity effects in poultry.

关 键 词：H7N9流感 免疫效果 血凝抑制试验 抗体检测 

分 类 号：S831.7[农业科学—畜牧学]