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作 者:刘毛平 周遵建 李杰 LIU Mao-ping;ZHOU Zun-jian;LI Jie(Department of Internal Medicine,Qingdao Licang District Central Hospital,Qingdao 266041,China;Qingdao Siliu North Road Community Health Service Center,Qingdao 266000,China)
机构地区:[1]青岛市李沧区中心医院内科,山东青岛266041 [2]青岛市四流北路社区卫生服务中心,山东青岛266000
出 处:《中国医药指南》2019年第26期12-13,共2页Guide of China Medicine
摘 要:目的探讨持续食用番薯治疗老年性便秘的临床研究效果。方法2018年1月至2018年6月诊治的慢性便秘患者92例,随机分为观察组与对照组,各46例。观察组,每日餐前30 min口服枸橼酸莫沙必利片5 mg,3次/天;每日中午饭中含蒸熟番薯(地瓜)2~3两。2周后停用莫沙必利。中午饭中含蒸熟番薯2~3两持续食用6个月。对照组,患者口服乳果糖口服溶液30 mL,1次/天。2周后停用。治疗期间每3 d观察1次。2周后,所有患者每2周回访1次,持续6个月。结果两组在治疗观察期间,观察组(A)发生1例急性心肌梗死,对照组(B)发生1例急性脑梗2例,均退出试验。不影响年龄,性别在统计学的无显著性差异。两组在药物治疗期间的并发症及停药时疗效统计学上无显著性差异。在后续3个月、6个月的观察中,A组的效果越来越优于B组。结论番薯在慢性老年性便秘的疗效维持及治疗作用上有很好效果,临床实践中有一定的应用价值。Objective To investigate the clinical effects of continuous consumption of ipomoea batatas for the treatment of senile constipation.Methods From January 2018 to June 2018,92 patients with chronic constipation were randomly divided into observation group and control group,46 cases in each.In the observation group,Mosapride citrate tablets 5 mg,3 times a day,30 minutes before the daily meal;steamed ipomoea batatas(sweet potato)2-3 two in the daily lunch.Mosapride was discontinued after two weeks.The lunch contains steamed ipomoea batatas 2-3 for two months.In the control group,the patient took oral lactulose oral solution 30 mL once daily.Deactivated after two weeks.Observed once every 3 days during treatment.After two weeks,all patients returned once every two weeks for six months.Results During the observation period,1 case of acute myocardial infarction occurred in the observation group(A),and 1 case of acute cerebral infarction occurred in the control group(B).There was no statistically significant difference in gender between age and gender.There were no statistically significant differences in the complications between the two groups during drug treatment and the efficacy of discontinuation.In the subsequent 3 months and 6 months of observation,the effect of group A was better than that of group B.Conclusion Ipomoea batatas has a good effect on the maintenance and treatment of chronic senile constipation,and it has certain application value in clinical practice.
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