副猪嗜血杆菌脂多糖的基因特征及其在致病过程中作用研究进展  

Progress on Gene Features of Haemophilus parasuis Lipopolysaccharide and Lts Role in Pathogenesis

作　　者：曾泽 张华琦[1,3,4] 桂干北 綦世金 刘杉杉 张斌 ZENG Ze;ZHANG Hua-qi;GUI Gan-bei;QI Shi-jin;LIU Shan-shan;ZHANG Bin(Tongren Vocational Technical College,Tongren,Guizhou,554300,China;College of Life Science and Technology,Southwest Minzu University,Chendu,Sichuan,610041,China;Collaborative Innovation Center of Guizhou Province Livestock and Poultry Healthy Breeding,Tongren,Guizhou,554300,China;Engineering Research Center of Safe and Efficient Application of Guizhou Province Feed Forage,Tongren,Guizhou,554300,China)

机构地区：[1]铜仁职业技术学院,贵州铜仁554300 [2]西南民族大学生命科学与技术学院,四川成都610041 [3]贵州省畜禽健康养殖协同创新中心,贵州铜仁554300 [4]贵州省饲料饲草安全与高效应用工程研究中心,贵州铜仁554300

出　　处：《动物医学进展》2019年第10期84-89,共6页Progress In Veterinary Medicine

基　　金：贵州省科技计划项目(黔科合基础[2019]1314号);铜仁市科技计划项目(铜市科研[2018]34号);贵州省星火计划项目(黔科合成转字[2015]5326-1号)

摘　　要：副猪嗜血杆菌(HPS)能够引起猪的脑膜炎、多发性浆膜炎、关节炎、急性肺炎和急性败血症为主要特征的猪革拉泽氏病。脂多糖(LPS)是革兰阴性菌外膜的主要成分,在致病机制中起着重要作用。论文对HPS的LPS结构、基因特征和致病机制进行综述,旨在为探索HPS LPS的相关毒力基因及对HPS LPS致病机制研究提供参考。Haemophilus parasuis(HPS)can cause Gl ser s disease,which is characterized by fibrinous polyserositis,arthritis,meningitis,acute pneumoniae and acute septicaemia.Lipopolysaccharide(LPS)is the major constituent of the outer membranes of Gram-negative bacteria and has a great influence on pathogenesis.In this article,the structure,gene feature and pathogenesis of HPS LPS were discussed,which is helpful to explore the virulence associated gene and the pathogenesis of HPS LPS.

关 键 词：副猪嗜血杆菌 脂多糖 基因特征 致病机制 

分 类 号：S852.612[农业科学—基础兽医学]