基于社区的2型糖尿病周围神经病变中医证候特征及发病因素调查分析  

Investigation and Analysis on TCM Syndrome Characteristics and Pathogenesis Factors of Type 2 Diabetic Peripheral Neuropathy Based on Community

作　　者：胡航 尤良震 林逸轩 江爱娟[1] 申国明[1] HUHang;YOU Liangzhen;LIN Yixuan;JIANG Aijuan;SHEN Guoming(Anhui University of Traditional Chinese Medicine,Hefei 230038,China;The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei 230031,China)

机构地区：[1]安徽中医药大学,安徽合肥230038 [2]安徽中医药大学第一附属医院,安徽合肥230031

出　　处：《云南中医学院学报》2019年第1期42-46,共5页Journal of Yunnan University of Traditional Chinese Medicine

基　　金：安徽省高等学校自然科学研究重大项目（KJ2018ZD029）

摘　　要：目的基于社区人群探讨2型糖尿病(T2DM)并发糖尿病周围神经病变(DPN)患者中医证候特征及发病因素调查。方法对T2DM并发DPN患者189例,使用中医证候量表分析DPN患者的中医证候特征及发病因素。结果(1)单证出现频率依次为气虚证102例(53.96%)、阴虚证89例(47.08%)、血瘀证69例(36.5%)、痰湿证49例(25.92%)、血虚证44例(23.28%)、火热证40例(21.16%)、阳虚证21例(11.11%);(2)轻度气虚证出现频率为60%,中度阴虚证、血瘀证和阳虚证出现频率分别为46.66%、44.44%、9%,重度阴虚证、血瘀证出现频率分别为55.88%、58.82%;(3)轻度单证出现率最高51.05%,中度、重度复合证出现频率分别为93.55%和100%;(4)证候组合形态有26种,轻度中气虚证出现率8例(17.02%),中度中气阴两虚出现率17例(18.27%),重度阴阳两虚血瘀证出现率10例(20.4%);(5)多因素logistic回归分析显示,病程、年龄以及多伦多量表得分高是阴阳两虚夹痰瘀证的危险因素。结论气虚证、阴虚证是发病率最高的中医证候,随着DPN病变程度的进展,中医证型从气阴两虚证往阴阳两虚夹痰瘀证转变,且患病病程、年龄以及多伦多评分高低是关键因素。Objective To investigate the characteristics and pathogenesis of TCM syndromes in patients with type 2 diabetes mellitus(T2DM)complicated with diabetic peripheral neuropathy(DPN).Methods From January 2018 to December 2018,189 patients with T2DM complicated with DPN were collected from the health service center of Tongling road and Sanlian street in Hefei city.The TCM syndrome scale was used to investigate and analyze the TCM syndrome characteristics of DPN patients as well as the pathogenic factors of the syndrome of deficiency of Yin and Yang combined with phlegm and dampness.Results(1)The frequency of single syndrome was 102 cases of qi deficiency(53.96%),89 cases of Yin deficiency(47.08%),69 cases of blood stasis(36.5%),49 cases of phlegm-dampness syndrome(25.92%),44 cases of blood deficiency syndrome(23.28%),40 cases of heat syndrome(21.16%),and 21 cases of Yang deficiency syndrome(11.11%).The frequency of moderate Yin deficiency,blood stasis and Yang deficiency increased significantly(46.66%,44.44%,9%).Severe Yin deficiency syndrome and blood stasis syndrome were the highest(55.88%,58.82%).(3)the occurrence rate of mild single syndrome was up to 51.05%,and the frequency of moderate and severe composite syndrome was up to 93.55%and 100%,respectively.(4)there are 26 types of syndrome combinations,with a relatively high incidence of mild mid-qi deficiency(8,17.02%).There were 17 cases(18.27%)with moderate qi and Yin deficiency.The incidence of severe deficiency of Yin and Yang and blood stasis syndrome was higher in 10 cases(20.4%).(5)multivariable logistic regression analysis showed,age and duration of Toronto scale score of Yin and Yang are two risk factors of phlegm and blood stasis syndrome.Conclusion Qi deficiency syndrome,Yin deficiency is the highest rates of TCM syndrome,with the progress of the DPN lesion degree,from qi and Yin deficiency syndrome of TCM syndrome types will be moving in the two virtual clip phlegm and blood stasis syndrome of Yin and Yang,and disease course,age and Toronto,score is the

关 键 词：2型糖尿病 糖尿病周围神经病变 中医证候 发病因素 社区卫生服务 

分 类 号：R259[医药卫生—中西医结合]