原子吸收分光光度法测定紫朱软膏中总汞的含量  

Determination of total mercury in zizhu ointment by atomic absorption spectrophotometry

作　　者：李西林[1] 柳国斌[2] 夏晶[3] 于鑫[1] LI Xilin;LIU Guobin;XIA Jing;YU Xin(School of Pharmacy,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Vascular Surgery,Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Food and Drug Inspection Office,Shanghai 200233,China)

机构地区：[1]上海中医药大学中药学院,上海201203 [2]上海中医药大学附属曙光医院血管外科,上海201203 [3]上海市食品药品检验所,上海200233

出　　处：《上海中医药杂志》2019年第10期97-99,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市科委科研计划项目(中药现代化)专项(ODZ1972800);上海市科委科研计划项目(16401902200)

摘　　要：目的对紫朱软膏中的总汞进行含量测定研究,为建立有效的质量控制方法提供依据。方法将样品经微波消解后,采用原子吸收分光光度法(AAS)测定紫朱软膏中的总汞的含量。结果建立的总汞测定方法线性关系为Y=0.001 8X+0.000 3,相关系数为0.999 9,加样回收率为92.02%~105.84%;测得紫朱软膏中总汞平均含量为3.13%,RSD为2.70%。结论本法为制定紫朱软膏的质量标准提供了切实可靠的依据。Objective To study the content determination of total mercury in Zizhu Ointment and facilitate the establishment of effective quality control methods. Methods After microwave digestion of samples, the content of total mercury in Zizhu Ointment was determined by atomic absorption spectrophotometry(AAS). Results The linear relationship of the established method was y=0.001 8x+0.000 3, the correlation coefficient was 0.999 9, and the recovery rate was 92.02%-105.84%. The average content of total mercury in Zizhu Ointment was 3.13% with RSD of 2.70%. Conclusion This method provides a practical and reliable basis for formulation of the quality standards of Zizhu Ointment.

关 键 词：原子吸收分光光度法 紫朱软膏 总汞 

分 类 号：R28[医药卫生—中药学]