miRNA与侵袭性垂体瘤相关性的中西医研究进展  

Advances in Research on the Relationship Between MicroRNAs and Invasive Pituitary Tumors in Traditional Chinese and Western Medicine Treatment

作　　者：张奇志 汪莹 张秋娟[1] ZHANG Qi-zhi;WANG Ying;ZHANG Qiu-juan(Yueyang Integrated Traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of TCM,Shanghai,China,200437)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院

出　　处：《河南中医》2019年第10期1601-1607,共7页Henan Traditional Chinese Medicine

基　　金：国家自然科学基金项目(30304117323)

摘　　要：西医治疗侵袭性垂体瘤以手术疗法、内分泌激素治疗及化疗等为主。中医治疗以辨病、辨证相结合为基本原则,以脾虚湿盛,肾气不足为本,痰凝、血瘀为标,标本兼治方能奏效。目前,对于具有恶性特质的侵袭性垂体瘤,中药作用人体miRNA以及中药提取物在miRNA水平抗肿瘤的机制仍有待进一步研究。Western medicine mainly treats invasive pituitary adenoma by surgery,endocrine hormone therapy and chemotherapy.While TCM treatment is based on the combination of disease differentiation and syndrome differentiation,regarding spleen deficiency and excessive dampness,insufficiency of kidney qi as the primary causes,phlegm coagulation and blood stasis as the secondary causes,and treating both of them can work.At present,for invasive pituitary adenomas with malignant characteristics,the anti-tumor mechanism of TCM on human microRNAs and TCM extracts at the level of microRNAs remains to be further studied.

关 键 词：侵袭性垂体瘤 MIRNA 手术疗法 激素疗法 化学疗法 中医药疗法 

分 类 号：R273.364[医药卫生—中西医结合]