含有吩恶嗪结构的双膦配体的合成工艺研究  

Synthesis of Diphosphine Ligand Containing Phenoxazine

作　　者：赵顺伟 周铎 李云飞 张垚 刘甜甜 陈辉 ZHAO Shun-wei;ZHOU Duo;LI Yun-fei;ZHANG Yao;LIU Tian-tian;CHEN Hui(Institute of Chemistry Henan Academy of Sciences,Zhengzhou 450002,Henan,China)

机构地区：[1]河南省科学院化学研究所有限公司

出　　处：《合成材料老化与应用》2019年第5期46-48,共3页Synthetic Materials Aging and Application

基　　金：河南省科技开放合作项目(182106000015);河南省科学院科研开发项目(18ZT03011,18ZS03009)

摘　　要：以2-氨基苯酚为原料,在碘的催化下首先合成吩恶嗪,然后经与叔丁基二甲基氯硅烷反应,正丁基锂锂化后与二苯基氯化磷反应,再经脱保护等步骤得到了4,6-双(二苯基膦)吩噁嗪,采用核磁和高分辨质谱对目标化合物进行了表征,并对反应过程的关键步骤进行了优化。Starting from 2-aminophenol as raw material,phenoxazine was first synthesized under the catalysis of iodine,then reacted with tert-butyldimethylchlorosilane.The intermediate was lithiated with n-butyllithium and reacted with diphenylphosphonium chloride.And after deprotection,4,6-bis(diphenylphosphino)phenoxazine was synthesized.The target compounds were characterized by NMR and high resolution mass spectrometry,and the key steps of the reaction process were optimized.

关 键 词：2-氨基苯酚 吩恶嗪 保护基 双磷配体 

分 类 号：TQ254[化学工程—有机化工]