急性低频感音神经性聋VEMP特点及分析  

Characteristics of vestibular evoked myogenic potentials in patients with acute low frequency sensorineural hearing loss

作　　者：吕哲[1] 张颖[1] 郭丽娇[1] 韩海霞[1] LV Zhe;ZHANG Ying;GUO Lijiao(Department of Otolaryngology,The Second Hospital of Hebei Medical University,Hebei,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院耳鼻咽喉科

出　　处：《河北医药》2019年第21期3237-3240,共4页Hebei Medical Journal

基　　金：河北省医学科学研究重点课题(编号:20160107)

摘　　要：目的观察急性低频感音神经性聋患者颈肌和眼肌前庭诱发肌源性电位(cVEMP、oVEMP)的引出率和各参数指标,探讨其临床诊断价值。方法选取2015年8月至2017年7月诊断为急性低频感音神经性聋的患者50例,行纯音听阈检测及cVEMP、oVEMP电位检测,分析对比患耳和对侧cVEMP、oVEMP的引出率和P1、N1潜伏期、波间期,并与正常听力志愿者(对照组)比较,分析前庭功能受损状况。结果 ALHL患者PTT图呈以低频听阈升高为特征的上升型曲线,表现为轻中度感音神经性聋。患耳在低频区听阈明显高于健侧和对照组,高频区听阈差异无统计学意义(P>0.05)。患耳、健耳和对照组的cVEMP电位引出率分别为64.0%(32/50)、88.0%(44/50)和100%(50/50),cVEMP引出率差异有统计学意义(P<0.05)。oVEMP电位引出率分别为86.0%(43/50)、96.0%(48/50)和96.0%(48/50),oVEMP引出率差异无统计学意义(P>0.05)。对患耳、健耳和对照组P1、N1和波间期、振幅等参数进行分析,差异均无统计学意义(P>0.05)。结论急性低频感音神经性聋患者前庭诱发肌源性电位的引出率最具有参考价值,波形参数大多正常或接近正常。Objective To observe the the response rate and characsteristeric of various parameters of cervical and ocular vestibular evoked myogenic potentials(cVEMP,oVEMP)in patients with acute low frequency sensorineural hearing loss(ALHL),and to explore their clinical diagnostic value.Methods Fifty patients with ALHL who were diagnosed in our hospital from August 2015 to July 2017 were enrolled as research group, and the other 50 healthy subjects were enrolled as control group.The pure tone threshold detection cVEMP and oVEMP electric potential detection were performed in both groups.The results(response rate,P1 latency,N1 latency,wave internals,amplitude) were observed and compared between the two groups to analyze the injury status of vestibular function of patients.Results The PTT in research group showed an upward curve characterized by elevated low-frequency hearing threshold,and presented as mild to moderate sensorineural deafness,and the hearing threshold of the affected ears in the low frequency area was significantly higher than that of contralateral ears and that in control group,but there was no significant difference in the high frequency area(P>0.05).The response rates of cVEMP potential were 64%(32/50),88%(44/50) and 100%(50/50),respectively in affected ears,contralateral ears and the control group.There were significant differences in the response rates of cVEMP(P<0.05).The response rates of oVEMP potential were 86%(43/50),96%(48/50)and 96%(48/50)in the affected ears,contralateral ears and the control group,respectively,there were no significant differences in the response rates of oVEMP(P>0.05). There were no significant differences in waveform,P1 latency,N1 latency,wave internals,amplitude among affected ears,contralateral ears and the control group(P>0.05).Conclusion The response rate of vestibular evoked myogenic potential in patients with acute low-frequency sensorineural hearing loss is of important reference value.The waveform parameters are mostly normal or close to normal.

关 键 词：急性低频感音神经性聋 前庭诱发肌源性电位 听阈 梅尼埃病 

分 类 号：R764.431[医药卫生—耳鼻咽喉科]