鼻内镜手术治疗慢性鼻-鼻窦炎的临床效果及相关影响因素分析  

Clinical effect of endoscopic sinus surgery in the treatment of chronic rhinosinusitis and analysis of related influencing factors

作　　者：王盈盈[1] 江琳艳[1] 杨徐静[1] 刘翠兰[1] WANG Ying-ying;JIANG Lin-yan;YANG Xu-jing;Liu Cui-lan(Department of Otolaryngology,the First Affiliated Hospital of Wenzhou Medical University,Zhejiang Wenzhou 325000,China)

机构地区：[1]温州医科大学附属第一医院耳鼻喉科

出　　处：《中国医刊》2019年第11期1234-1237,共4页Chinese Journal of Medicine

摘　　要：目的探讨鼻内镜手术治疗慢性鼻-鼻窦炎(chronic rhinosinusitis,CRS)的临床效果,并分析影响临床效果的相关因素。方法选取2016年2月至2018年2月温州医科大学附属第一医院收治的265例CRS患者为研究对象,所有患者均行鼻内镜手术治疗,收集患者的相关资料,包括年龄、性别、文化程度、病程、住院时间、药物治疗情况、吸烟、饮酒、有无变应性鼻炎、临床分型、鼻息肉、鼻腔粘连、疼痛数字评分法(numerical rating scale,NRS)评分、Lund-Mackay鼻窦CT评分、是否复发、Lund-Kennedy鼻内镜评分、治疗依从性。评估术后6个月的临床治疗效果,同时采用logistic回归法分析影响临床治疗效果的影响因素。结果265例CRS患者,病情完全控制率为88.30%(234/265),部分控制率为7.55%(20/265),未控制率为4.15%(11/265);logistic回归分析显示,是否合并变应性鼻炎、鼻息肉、NRS评分、Lund-Mackay鼻窦CT评分、有无复发、Lund-Kennedy鼻内镜评分以及治疗依从性是影响临床治疗效果的主要因素。结论鼻内镜手术治疗CRS能够获得较好的临床效果,疗效与有无复发、临床分型、NRS评分、鼻窦CT评分、鼻内镜评分等因素有关。Objective To observe the clinical therapeutic effect of endoscopic rhinosinusitis(CRS),and analyze the related factors affecting the clinical effect.Method A total of 265 CRS patients admitted to the department of otolaryngology,the first affiliated hospital of wenzhou medical university from February 2016 to February 2018 were selected,all of whom were treated with nasal endoscopic surgery,with this as the research object,relevant data of 265 CRS patients were collected,including age,gender,education level,course of disease,length of stay,medical treatment,smoking,drinking,presence of allergic rhinitis,clinical classification,nasal polyps,nasal adhesion,NRS score,Lund-Mackay sinus CT score,recurrence,Lund-Kennedy nasal endoscopic score,and treatment compliance.to evaluate the clinical treatment effect at 6 months after surgery.Meanwhile,Logistic regression method was used to analyze the influencing factors of clinical treatment effect.Result In 265 CRS patients,the complete control rate was 88.30%(234/265).The partial control rate reached 7.55%(20/265).The control rate was 4.15%(11/265).Logistic regression analysis showed that the main factors affecting the clinical effect were whether allergic rhinitis(AR)was complicated,nasal polyps,NRS pain score,Lund-Mackay sinus CT score,whether there was recurrence,Lund-Kennedy endoscopic score and treatment compliance.Conclusion Nasal endoscopic surgery for CRS can achieve good clinical effects,which are related to the presence or absence of recurrence,clinical typing,NRS pain score,sinus CT score,nasal endoscopic score and other factors.

关 键 词：鼻内镜手术 慢性鼻-鼻窦炎 疗效 影响因素 完全控制率 LOGISTIC回归分析 

分 类 号：R765.9[医药卫生—耳鼻咽喉科]