药用植物中GRAS转录因子的功能研究进展  

Research progress on the functions of GRAS transcription factors in medical plants

作　　者：刘云辉 李珅 王洋 羊健[2] 周伟 沈亚芳 LIU Yunhui;LI Shen;WANG Yang;YANG Jian;ZHOU Wei;SHEN Yafang(The Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province,School of Agriculture and Food Science,Zhejiang A&F University,Hangzhou 311300,Zhejiang,China;Key Laboratory of Biotechnology in Plant Protection of Ministry of the People’s Republic of China and Zhejiang Province,Zhejiang Academy of Agricultural Science,Hangzhou 310021,Zhejiang,China)

机构地区：[1]浙江农林大学农业与食品科学学院浙江省农产品品质改良技术研究重点实验室,浙江杭州311300 [2]浙江省农业科学院农业部/浙江省植保生物技术重点实验室,浙江杭州310021

出　　处：《浙江农林大学学报》2019年第6期1233-1240,共8页Journal of Zhejiang A&F University

基　　金：农业部/浙江省植物保护生物技术重点实验室开放基金资助项目（2010DS700124-KF1607）

摘　　要：GRAS是重要的植物转录调控因子,依据结构特征分为10个主要亚家族。目前已在许多药用植物和其他植物中开展了GRAS转录因子的研究,发现其家族成员广泛参与生长、发育、非生物胁迫响应、信号转导相关应答、初级和次级代谢等过程。对GRAS转录因子的结构特征、功能作用以及在药用植物中的研究进展进行了综述。结合自身研究对药用植物研究前景进行分析后指出,后续研究可以聚焦以下几个方面:首先重点解析每个GRAS亚家族保守结构域的功能;其次是分析GRAS蛋白N端可变序列的进化特征;再者是解析GRAS家族成员调控品质和响应逆境胁迫的分子调控网络;最后是解析表观遗传调控与GRAS的协同作用模型。GRAS is a very important transcription factors(TFs)family in plants and can be classified into ten subfamilies.There has been numerous research on elucidating the functions of GRAS TFs in medical plants and other plants.The existing research indicates that this kind of TFs participate extensively in the process of growth,development,response to abiotic stress,signal transduction,primary and secondary metabolism,and so on.This study reviews the research progresses on GRAS TFs around the structure features,functional roles,and new research advances.After analyzing the research prospect of medicinal plants in combination with our own research,the paper proposes the following directions for future research:firstly,the function of each GRAS subfamily conserved structural domain should be analyzed;secondly,the evolution characteristics of GRAS protein N-terminal variable sequences should be elucidated;thirdly,the molecular regulatory network about how the GRAS families regulate the quality and respond to adversity stress should be analyzed;finally,the cooperative regulation model of epigenetic modification and GRAS should be studied.This study provides an important reference to conduct innovative research works on Chinese medical plants.[Ch,1 fig.2 tab.39 ref.]

关 键 词：中药学 药用植物 转录因子 生长发育 逆境胁迫 信号转导 

分 类 号：R282[医药卫生—中药学]