双参数3D ASL联合MRA对单侧大脑中动脉闭塞后侧支循环代偿评估中的应用价值研究  

Preliminary study of double-parameter 3D-ASL combined with MRA to evaluation collateral circulation in patients with unilateral middle cerebral artery occlusion

作　　者：于秀英[1] 隋汝德 何勇[2] 赵小燕[3] 刘松国[1] 韩广[1] 韩召春[1] 孟祥福[1] Yu Xiuying;Sui Rude;He Yong;Zhao Xiaoyan;LiuSongguo;Han Guang;Han Zhaochun;Meng Xiangfu(Department of Medical Imaging,Linyi Hospital of Traditional Chinese Medicine,Linyi,Shandong 276000,China;Linyi Chinese Medicine Hospital Orthopaedics,Linyi,Shandong 276000;Linyi City Chinese Medicine Hospital Pharmacy Division,Linyi,Shandong 276000;Linyi City Central Hospital Medical Imaging Division,Linyi,Shandong 276400,China)

机构地区：[1]临沂市中医医院医学影像科,山东临沂276000 [2]临沂市中医医院骨科,山东临沂276000 [3]临沂市中医医院药剂科,山东临沂276000 [4]临沂市中心医院医学影像科,山东临沂276400

出　　处：《影像研究与医学应用》2019年第21期31-32,共2页Journal of Imaging Research and Medical Applications

基　　金：山东省医药卫生科技发展计划（2018WS390）

摘　　要：目的:探究双参数3D动脉自旋标记灌注成像(3D A SL)技术联合磁共振血管成像(MRA)在单侧大脑中动脉(MCA)闭塞后的侧支循环代偿评估中的应用价值。方法:收集单侧MCA闭塞的患者38例,测定双侧MCA供血区脑血流量(CBF),进行统计学分析。结果:单侧MCA闭塞患者患侧CBF在PLD 1525ms组与2525ms组具有显著统计学差异,而健侧两组之间无统计学差异。结论:双参数3D ASL联合3D-TOF-MRA在评估单侧MCA闭塞后侧支循环代偿评估中具有很重要的临床价值。Objective To investigate the application of double-parameter 3D-ASL technique combined with MRA in evaluating the collateral circulation in patients with unilateral middle cerebral artery occlusion.Methods 38 patients with occlusion of the middle cerebral artery were enrolled.Cerebral blood flow(CBF)in bilateral MCA blood supply areas was measured and analyzed statistically.Results There was statistically significant difference in CBF value of occluded cortical area between measurements by PLD=1525 ms group and by PLD=2525 ms group.There was no significant difference in CBF value of contralateral normal cerebral area between these two groups.Conclusion Double-parameter 3D-ASL combined with MRA can accurately evaluate collateral circulation in patients with unilateral middle cerebral artery occlusion.It has very important clinical value.

关 键 词：动脉自旋标记灌注成像 双标记延迟时间 磁共振血管成像 单侧大脑中动脉闭塞 侧支循环代偿 

分 类 号：R445[医药卫生—影像医学与核医学]