桑白皮药材的品质检测及质量标准  

Quality Detection and Quality Standard of Mori Cortex Medicinal Materials

作　　者：刘一涵[1] 田云刚[1] 郭洪伟 王建霞[1] 魏华[1,2] LIU Yihan;TIAN Yungang;GUO Hongwei;WANG Jianxia;WEI Hua(College of Biology and Environmental Science,Jishou University,Jishou 416000,Hunan China;Tujia Medicine Research Center in Hunan,Jishou 416000,Hunan China)

机构地区：[1]吉首大学生物资源与环境科学学院,湖南吉首416000 [2]湖南省土家医药研究中心,湖南吉首416000

出　　处：《吉首大学学报（自然科学版）》2019年第5期45-52,共8页Journal of Jishou University(Natural Sciences Edition)

基　　金：中医药行业科研专项“中药饮片质量保障系统研究(一)”资助项目(201507002);国家自然科学基金青年科学基金项目(81403088);吉首大学校级科研项目资助(JDY1858,JDY19049);吉首大学研究生科研创新项目资助(JGY201927)

摘　　要：采用薄层色谱法(TLC)对桑白皮的桑皮苷A、桑辛素、桑酮G进行了定性鉴别,并根据2015年版中国药典方法测定了不同产地不同生源桑白皮中水分、总灰分、酸不溶性灰分和浸出物,同时采用高效液相法(HPLC)测定了桑白皮中的桑皮苷A.结果表明,桑白皮中桑皮苷A、桑辛素、桑酮G斑点清晰、特征明显.最终建议桑白皮药材质量标准(以质量分数计)为:水分不超过13%,总灰分不超过9%,酸不溶性灰分不超过2.5%,水溶性热浸浸出物不得低于25%,以干燥品计,桑皮苷A质量分数不低于0.91%.Mulberroside A,morusin,and kuwanon G in Mori Cortex were qualitatively determined by thin layer chromatography(TLC),and the content of moisture,total ash,acid insoluble ash and extract in Mori Cortex from different origins were determined according to the methods in Chinese Pharmacopoeia of 2015 edition;in addition,the content of mulberroside A was determined by high performance liquid chromatography(HPLC).The results showed that the spots of mulberroside A,morusin,and kuwanon G were clear and distinctive.The quality standard(by mass fraction)of Mori Cortex medicinal materials is suggested:moisture should be less than 13%,total ash within 9%,acid insoluble ash no more than 2.5%,water soluble extract obtained by hot dip method no less than 25%,mulberroside A calculated on dried sample no less than 0.91%.

关 键 词：桑白皮 药材品质:质量标准 桑皮苷A 

分 类 号：R284[医药卫生—中药学]