SWI及~1H-MRS在鉴别WHO II^IV级脑胶质瘤中的应用  

Application of SWI and ~1H-MRS in the Identification of WHO II to IV Gliomas

作　　者：杜常月 苗娜 齐旭红 温智勇 DU Changyue;MIAO Na;QI Xuhong;WEN Zhiyong(Department of Radiology,Electric Power Teaching Hospital,Capital Medical University,Beijing 100073,China)

机构地区：[1]首都医科大学电力教学医院放射科

出　　处：《中国医疗设备》2019年第11期82-85,共4页China Medical Devices

基　　金：国家电网公司科技项目（O2017017）

摘　　要：目的评价磁敏感加权成像(Susceptibility Weighted Imaging,SWI)及氢质子波谱(1H Magnetic Resonance Spectroscopy,1H-MRS)成像在鉴别各级脑胶质瘤中的诊断价值。方法按照WHO分级方法将81例脑胶质瘤患者分为3组:Ⅱ级30例,Ⅲ级13例,Ⅳ级38例。所有患者均于术前完成SWI及1H-MRS成像,并经过术后组织病理学证实。通过后处理测量SWI及1H-MRS各个参数值,并进行统计学分析。结果rNAA在鉴别Ⅱ级与Ⅲ级中有统计学意义(P<0.05)。r Cho/NAA、r NAA/Cr在鉴别Ⅱ级与Ⅲ级、Ⅱ级与Ⅳ级中有统计学意义(P<0.05)。SWI在各组间均具有显著的统计学差异(P<0.05)。联合两种技术的ROC曲线下面积AUC、敏感性和特异性均大于单独应用某一种技术。结论联合SWI及1H-MRS对脑胶质瘤分级的诊断效能大于单独应用某一种技术;SWI比1H-MRS的诊断效能高。Objective To evaluate the value of susceptibility weighted imaging(SWI)and 1 H magnetic resonance spectroscopy(1 H-MRS)in diagnosis of glioma.Methods According to WHO classification method,81 patients with glioma were divided into three groups:30 cases of grade Ⅱ,13 cases of grade Ⅲ and 38 cases of grade Ⅳ.All patients underwent SWI and 1 H-MRS imaging before operation,and were confirmed by postoperative histopathology.All parameters of SWI and 1 H-MRS were measured by post-processing,and then were analyzed statistically.Results Parameter r NAA had statistical significance in differentiating grade Ⅱ from grade Ⅲ(P<0.05).r Cho/NAA and r NAA/Cr had statistical significance in differentiating grade Ⅱ from grade Ⅲand grade Ⅱ from grade Ⅳ(P<0.05).There were significant statistical differences in SWI among groups(P<0.05).By combining these two techniques,the AUC,sensitivity and specificity were greater than the application of a single technique.Conclusion The diagnostic efficiency of combined SWI and MRS in grading of glioma is higher than that of single technique.SWI has higher diagnostic efficacy than 1H-MRS.

关 键 词：脑胶质瘤 磁敏感加权成像 氢质子波谱 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R739.4[医药卫生—诊断学]