L-丙交酯高浓度长晶体的合成  

Synthesis of High Content of L-Lactide with Long Crystals

作　　者：刘洋 胡斌 龚成琳 王秀美 马建洋 张奇 LIU Yang;HU Bin;GONG Cheng-lin;WANG Xiu-mei;MA Jian-yang;ZHANG Qi(School of Chemistry and Chemical Engineering,Beijing Institute of Technology,Beijing 100081,China)

机构地区：[1]北京理工大学化学与化工学院

出　　处：《北京理工大学学报》2019年第10期1097-1100,共4页Transactions of Beijing Institute of Technology

基　　金：国家教育部教育教学改革专项基金资助项目(1330012051803);北京理工大学化学与化工学院教改专项资助项目(31000123A1801)

摘　　要：为得到L-丙交酯浓度较高的D,L-丙交酯晶体混合物,本文研究了乳酸为原料,用减压蒸馏法合成丙交酯的优化工艺条件.对催化剂的选择和用量、反应时间、反应温度等工艺进行了考察和研究,确定了丙交酯的优化反应工艺条件.采用优化反应工艺条件聚合得到晶体长度约为5~10μm的长条状D,L-丙交酯晶体混合物,混合物中L-丙交酯的浓度较高,为76.5%.In order to obtain D,L-lactide with higher content of L-lactide,the optimum conditions for the synthesis of D,L-lactide by vacuum distillation were studied.Investigating and studying the catalyst selection and dosage,reaction time,reaction temperature and other processes,the optimal process conditions for lactide were determined.Polymerization was carried out under optimized reaction conditions,obtaining a long strip of D,L-lactide crystals with a crystal length of about 5~10μm.The content of L-lactide in the mixture can be up to 76.5%.

关 键 词：L-丙交酯 减压蒸馏法 优化工艺 浓度 

分 类 号：O626[理学—有机化学]