445例利多卡因注射液不良反应文献分析  

Literature Analysis of 445 Cases of Adverse Reaction Cases Induced by Lidocaine Injection

作　　者：沈晓华[1] 罗凌凤[2] 林强[1] 窦元元[3] SHEN Xiao-hua;LUO Ling-feng;LIN Qiang;DOU yuan-yuan(Center for ADR Monitoring of Fujian,Fuzhou 350003,China;Fujian Medical University,Fuzhou 350108,China;Fuzhou General Hospital of Nanjing Military Region,Fuzhou 350025,China)

机构地区：[1]福建省药品不良反应监测中心,福建福州350003 [2]福建医科大学,福建福州350108 [3]南京军区福州总医院,福建福州350025

出　　处：《海峡药学》2019年第10期247-249,共3页Strait Pharmaceutical Journal

摘　　要：目的探讨利多卡因注射液不良反应的特点。方法以“利多卡因”、“反应”、“致”、“过敏性休克”等为检索词,检索涉及利多卡因注射液不良反应相关文献,对纳入的文献进行信息提取和统计分析。结果利多卡因注射液不良反应发生时间多在30min内,主要表现为毒性反应、过敏反应等。结论有必要对利多卡因注射液所致不良反应进行再评价,并在此基础上对说明书进行修改和完善。OBJECTIVE To study the characteristics of the adverse reaction induced by lidocaine injection.METHODS Using“lidocaine”,“reaction”,“to”,and“anaphylactic shock”as key words,search for literature related to adverse reactions of lidocaine injection.RESULTS The adverse reactions of lidocaine injection occurred within 30min.Lidocaine injection may lead to adverse reactions such as toxic reaction and allergic reaction.CONCLUSION It is necessary to re-evaluation the risk of adverse reactions caused by lidocaine injection.On this basis,modifying the drug instructions.

关 键 词：利多卡因 不良反应 文献分析 

分 类 号：R969.3[医药卫生—药理学]