2015年四川省人体肠道原虫感染现状调查  

Prevalence of human intestinal protozoan infections in Sichuan Province in 2015

作　　者：罗静雯[1] 田洪春[1] 谢红[1] 钟波[1] 刘阳[1] 陈漪澜[1] 李黎[1] LUO Jing-wen;TIAN Hong-chun;XIE Hong;ZHONG Bo;LIU Yang;CHEN Yi-lan;LI Li(Sichuan Center for Disease Control and Prevention,Chengdu 610041,China)

机构地区：[1]四川省疾病预防控制中心

出　　处：《中国寄生虫学与寄生虫病杂志》2019年第5期583-587,共5页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：目的了解四川省人体肠道原虫感染现状。方法根据全国人体重点寄生虫病现状调查方案和实施细则,于2015年4-6月,采用分层整群随机抽样方法,选取四川省5个生态区的15个调查县(市、区)45个调查点。调查对象为各调查点0岁以上的农村常住居民,每个调查点调查人数不少于250人。采集受检对象粪样,采用卢戈氏碘液染色法(一粪一检)检查粪样原虫包囊,采用生理盐水涂片法(一粪一检)检查新鲜稀粪或脓血便的滋养体。应用SPSS 23.0软件进行统计学分析,感染率通过χ^2检验进行比较。结果共调查11403人,肠道原虫感染率为2.0%(223/11403)。共发现9种原虫:溶组织内阿米巴、结肠内阿米巴、蓝氏贾第鞭毛虫、人芽囊原虫、微小内蜒阿米巴、哈门氏内阿米巴的感染率分别为0.2%(22/11403)、0.7%(78/11403)、0.1%(9/11403)、0.5%(60/11403)、0.6%(67/11403)、0.2%(17/11403),结肠小袋纤毛虫、布氏嗜碘阿米巴、肠内滴虫的感染病例数分别为2、1和1例。江河源区-甘南生态区人群原虫感染率最高,为6.5%(148/2278);四川盆地生态区感染率最低,为0.4%(10/2289);不同生态区肠道原虫感染率差异有统计学意义(P<0.01)。马尔康县人群原虫感染率最高,为10.2%(102/1001);甘孜县感染率次之,为6.1%(46/755);不同县(市、区)原虫感染率差异有统计学意义(P<0.01)。男、女肠道原虫感染率分别为1.9%(97/5247)和2.1%(126/6156),差异无统计学意义(P>0.05)。20~29岁年龄组肠道原虫感染率最高,为2.8%(23/813);≥80岁年龄组人群感染率为0;不同年龄组人群肠道原虫感染率差异无统计学意义(P>0.05)。文盲人群肠道原虫感染率最高,为3.2%(73/2317);大专、大学以上人群感染率为0;不同文化程度人群肠道原虫感染率差异有统计学意义(P<0.01)。牧民原虫感染率最高,为4.8%(20/421);学生感染率次之,为2.0%(30/1491);不同职业人群肠道原虫感染率差异无统计学意义(P>0.05)。Objective To understand the current status of human intestinal protozoan infections in Sichuan Province.Methods An epidemiological survey was carried out in Sichuan Province according to the Protocol of National Survey Scheme on Major Human Parasitic Diseases from April to June,2015.Total 45 survey sites were selected from 15 counties(cities and districts)within 5 ecological zones of Sichuan by using a stratified sampling method.No less than 250 rural permanent villagers in each site were enrolled in the survey and the fecal sample was collected from each participant.The protozoan cysts in the feces were examined by Lugol’s iodine staining method(one check for each sample).The protozoan trophozoites were examined only in the fresh diarrheal or bloody fecal samples using saline direct smear method(one check for each sample).Each fecal sample was examined once.SPSS 23.0 software was used for statistical analysis.The prevalence difference among the different groups of people was compared byχ^2 test.Results Total 11403 people were investigated.The overall prevalence of intestinal protozoan infections was 2.0%(223/11403)province-wide.Total 9 protozoan species were identified in infected people including Entamoeba histolytica(0.2%,22/11403),E.coli(0.7%,78/11403),Gardia lamblia(0.1%,9/11403),Blastocystis hominis(0.5%,60/11403),E.hartmani(0.2%,17/11403)and Endolimax nana(0.6%,67/11403).Two cases of Balantidium coli,one case of each Iodamoeba butschlii and Embadomonas intestinalis were identified.The highest prevalence of intestinal protozoan infections was identified in areas of Source of rivers-Southern Gansu ecological zone(6.5%,148/2278),and the lowest prevalence was identified in Sichuan basin zone(0.4%,10/2289).There was a significant difference in the prevalence of protozoan infections among different ecological zones(P<0.01).The highest prevalence of intestinal protozoan infections was identified in Markam County(10.2%,102/1001),followed by Ganzi County(6.1%,46/755).There was significant difference in the preva

关 键 词：肠道原虫 感染现状 四川省 

分 类 号：R532.1[医药卫生—内科学]