网膜素在神经关联疾病中的生物标记物作用  

Biomarker Effect of Omentin in Neural-related Diseases

作　　者：史欢欢 李斌[1] 陈霞[1] 赵宁[1,2] 牛晓晨 高啟伟 李武 史文珍 田晔 GAO Qi-wei;LI Wu;SHI Wen-zhen;TIAN Ye(The Department of Neurology,Xi’an No.3 Hospital,the Affiliated Hospital of Northwest University,Xi’an 710018,Shaanxi,China;School of Medicine,Yan’an University,Yan’an 716000,Shaanxi,China;The College of Life Sciences,Northwest University,Xi’an 710069,Shaanxi,China)

机构地区：[1]西北大学附属医院/西安市第三医院神经内科,中国陕西西安710018 [2]延安大学医学院,中国陕西延安716000 [3]西北大学生命科学学院,中国陕西西安710069

出　　处：《生命科学研究》2019年第5期407-411,共5页Life Science Research

基　　金：国家自然科学基金资助项目(81660210);陕西省重点研发计划项目(2018SF-107);西安市科技计划项目(2017114SF/YX008(3));西安市卫生和计划生育委员会资助项目(J201701002,J201801013)

摘　　要：网膜素(omentin)是一种新型的脂肪因子,由内脏脂肪组织分泌。研究发现,网膜素在脑梗死、成神经细胞瘤、多发性硬化等神经关联疾病中发挥着重要作用,并与疾病的发生、发展具有良好相关性。因此,网膜素或可成为神经关联疾病的生物标记物,为相关疾病的诊断、治疗和预后评估提供新指标。Omentin is a novel adipokine secreted by visceral fat tissue. Recent studies have found that omentin plays an important role in neurological diseases such as cerebral infarction, neuroblastoma and mul-tiple sclerosis, and that it is well correlated with the occurrence and development of these diseases. There-fore, omentin may be used as a biomarker and a new indicator for diagnosis, treatment, and prognosis as-sessment of some neurological diseases.

关 键 词：网膜素 生物标记物 脑梗死 成神经细胞瘤 多发性硬化骨质改变 

分 类 号：Q426[生物学—神经生物学] R363.14[生物学—生理学]