检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:金蔚涛 赵阳 张玉坤 叶讯 曾春[2] 王嵘[2] Jin Weitao;Zhao Yang;Zhang Yukun;Ye Xun;Zeng Chun;Wang Rong(Department of Neurosurgery,Peking University International Hospital,Beijing 102206,China;Department of Neurosurgery,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China)
机构地区:[1]北京大学国际医院神经外科,北京102206 [2]首都医科大学附属北京天坛医院神经外科,北京100070
出 处:《中华医学杂志》2019年第39期3073-3076,共4页National Medical Journal of China
摘 要:目的回顾性分析围手术期使用双联抗血小板治疗冠心病合并颈动脉狭窄患者行颈动脉内膜剥脱手术(CEA)的安全性。方法回顾分析了2017年1月至2019年3月期间于北京大学国际医院就诊的冠心病颈内动脉狭窄患者,共86例。86例均接受CEA,并在围手术期内持续双联抗血小板治疗。通过评估该组患者围手术期急性冠状动脉综合征(急性ST段抬高性心肌梗死、急性非ST段抬高性心肌梗死和不稳定性心绞痛)发生率、症状性或无症状性缺血性脑血管事件发生率、症状性或无症状性脑出血事件发生率和术后颈部血肿发生率,探讨双联抗血小板治疗冠心病合并颈动脉狭窄患者接受CEA之类的安全性。结果本组患者中围手术期急性冠状动脉综合征发生率为0,症状性脑梗死发生率为0,无症状性脑梗死发生率为8.1%(7/86);无症状或症状性脑出血发生率为0,颈部血肿发生率为13.9%(13/86)。术后30 d随访86例患者的改良RANKIN量表,均<3分,颈部血肿均经保守治疗自行恢复;无神经功能缺损或死亡。结论冠心病合并颈动脉狭窄患者在接受双联抗血小板治疗的同时行CEA,并未增加围手术期缺血性心脑血管事件的发生率,虽然增加了术区血肿的发生率,但并未明显增加颅内出血事件的发生率,提示,对于冠心病合并颈动脉狭窄患者在双联抗血小板药物治疗期内接受CEA是安全的。Objective To study the safety of dual antiplatelet therapy prior to carotid endarterectomy in the patients with carotid artery stenosis and Coronary Artery Accident.Methods We review 86 patients with carotid artery stenosis and Coronary Artery Accidents who admitted in Peking University International Hospital between 2017 January and 2019 March.The 86 patients undergo carotid endarterectomy with dual antiplatelet therapy.We evaluate the safety of carotid endarterectomy dunring the dual antiplatelet thrapy by analyzing the incidence of acute coronary syndrome,ischemic cerebrovascular accident,intracranial hemorrhage,and regional hematoma.Results From 2017 January to 2019 March,86 patients with carotid artery stenosis and Coronary Artery Accident continued dual antiplatelet therapy prior to carotid endarterectomy.The incidence of main perioperative complications were as follows:acute coronary syndrome:0;asymptomatic ischemia cerebrovascular accident:8.1%(7/86);symptomatic ischemia cerebrovascular accident:0;intracranial hemorrhage:0;neck hematoma:13.9%(13/86).All the patients were followed 30 days after the procedure.The modify Rakin Scale of the patients were all<3.The local hematoma were all recovered automatically without treatment and the perioperative mortality and morbidity was 0.Conclusion For the patients with carotid artery stenosis and Coronary Artery Accidents,carotid endarterectomy under dual antiplatelet therapy was a safe choice.
关 键 词:颈动脉狭窄 冠状动脉狭窄 颈动脉内膜剥脱术 双联抗血小板治疗
分 类 号:R54[医药卫生—心血管疾病]
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.117