成人股骨CT建模及解剖学参数三维自动测量  

Adult femur CT modeling and 3D automatic measurement of anatomical parameters

作　　者：薛磊 李乾 胡刚峰 沈磊[1] 李柳炳[1] 金志高[1] 朱忠林 谢宗刚[1] Xue Lei;Li Qian;Hu Gangfeng;Shen Lei;Li Liubing;Jin Zhigao;Zhu Zhonglin;Xie Zonggang(Department of Orthopedics,the Second Affiliated Hospital of Soochow University,Suzhou 215004,China)

机构地区：[1]苏州大学附属第二医院骨科,苏州215004

出　　处：《中华医学杂志》2019年第39期3093-3099,共7页National Medical Journal of China

基　　金：国家自然科学青年基金(81803266);江苏省自然科学青年基金(BK20180226);苏州市科技局医疗卫生应用基础研究(SYS201626、SYSD2018107)。

摘　　要：目的通过成人股骨CT数据精确重建三维模型,并实现股骨解剖学参数自动化测量,研究国人股骨解剖学参数特点。方法在148例成年患者中应用Mimics17.0软件根据CT数据实行建模,把建成的模型导入Geomagic Studio软件中,提取股骨解剖学标志建立三维坐标系,统一坐标系;利用Matlab软件自编程序,采用最近点迭代ICP算法和解剖学标志点的三维自动提取算法进行精确定位,自动测量股骨解剖学参数,最后对数据进行分析比较。研究数据采用独立样本t检验进行比较。结果本组股骨髁左右径男性为(84.1±3.6)mm,女性为(74.8±3.3)mm;股骨髁前后径男性为(66.5±3.7)mm,女性为(61.2±3.5)mm;球头直径男性为(48.8±2.1)mm,女性为(43.4±2.2)mm,差异均有统计学意义(t=16.21、8.84、15.20,均P<0.05);而股骨矩弧度半径男性为(112.5±24.5)mm,女性为(124.7±19.2)mm(t=3.30,P=0.002)。颈干角男性为124.9°±4.0°,女性为126.1°±5.5°(t=1.40,P>0.05)。随着身高增长,大部分解剖参数均随着增加。结论股骨解剖参数三维自动测量数据较手动测量重复性高、精度高。建立和丰富股骨解剖数据库,设计研发符合国人的内固定产品十分必要。Objective To reconstruct a 3D model from adult femur CT scan data and automate a measurement of femoral anatomical parameters to study the characteristics of Chinese femur anatomical parameters.Methods Using Mimics17.0,models from the CT data of 148 adult patients were established.The completed model was imported into Geomagic Studio and the anatomical landmarks of the femur were extracted to establish 3D coordinate system and unified coordinate system.Programmed with Matlab,using the nearest point iterative ICP algorithm and the 3D automatic extraction algorithm of anatomical landmarks to provide precision positioning,the femoral anatomical parameters were automatically measured and analyzed.The data were compared by using independent sample t test.Results In this group,the diameter of the male femoral condyle was(84.1±3.6)mm,and it was(74.8±3.3)mm in the female;the anteroposterior diameter of the male femoral condyle was(66.5±3.7)mm,and it was(61.2±3.5)mm in the female;the diameter of the male ball head was(48.8±2.1)mm and it was(43.4±2.2)mm in the female;the differences between the two genders were all statistically significant(t=16.21,8.84,15.20,all P<0.05).The male femoral moment radius was(112.5±24.5)mm,and it was(124.7±19.2)mm in the female(t=3.30,P=0.002).The neck angle in male participants was 124.9°±4.0°,and it was 126.1°±5.5°in the female(t=1.40,P>0.05).As the height growed,most of the anatomical parameters increased accordingly.Conclusions The 3D automatic measurement of femoral anatomical parameters is more reproducible and accurate than manual measurement.It is necessary to establish and enrich the femoral anatomical database to design and develop internal fixation products that meet the needs of Chinese people.

关 键 词：股骨 临床解剖学 自动测量 假体设计 

分 类 号：R68[医药卫生—骨科学]