胶原/甘油与胶原/异丙醇共混溶液的热行为比较(Ⅰ)——基于多重升温速率的“无模式函数法”动力学分析  

Comparison of thermal behaviors of collagen/glycerol and collagen/2-propanol blend solutions (Ⅰ): Model-free kinetic analysis based on multiple heating rates

作　　者：刘文涛[1,2] 王超 LIU Wentao;WANG Chao(The Key Laboratory of Leather Chemistry and Engineering(Sichuan University),Ministry of Education,Chengdu 610065,China;National Engineering Laboratory for Clean Technology of Leather Manufacture,Sichuan University,Chengdu 610065,China)

机构地区：[1]皮革化学与工程教育部重点实验室(四川大学),四川成都610065 [2]制革清洁技术国家工程实验室(四川大学),四川成都610065

出　　处：《中国皮革》2019年第11期1-6,共6页China Leather

基　　金：国家自然科学基金(21606156)

摘　　要：研究比较了胶原/甘油与股原/异丙醇共混溶液的热变性动力学行为。采用差示扫描量热仪考察了胶原热变性温度随升温速率的依赖性,用3种基于多重升温速率的“无模式函数法”(Kissinger法、Friedman和0FW等转化率法),对比分析了共混胶原溶液的热变性活化能及其随热反应进行的变化规律。结果表明:甘油和异丙醇诱导肢原的热行为发生改变,胶原/甘油与股原/异丙醇共混溶液的热变性过程都是多步复杂反应,前者体现了更好的热稳定性,而后者的热变性动力学行为更加复杂。鉴于等转化率法对于研究复杂动力学过程的局限性,有必要进一步结合采用模式函数拟合法,探究醇类物质对胶原热变性的影响。The thermal denaturation kinetics of collagen/glycerol and collagen/2-propanol blend solutions were studied.The dependence of thermal denaturation temperatures of collagen on heating rates was investigated by differential scanning calorimetry.Three kinds of"model-free methods"based on multiple heating rates(Kissinger method,Friedman and OFW isoconversional methods)were used to analyze and compare the thermal denaturation activation energy of the blend solutions and its variation with thermal reaction.The results show that the thermal behavior of collagen changes due to its interaction with glycerol and 2-propanol.The thermal denaturation processes of collagen/glycerol and collagen/2-propanol blend solutions are multi-step complex reactions.The former solution shows better thermal stability,while the latter one shows more complicated thermal denaturation kinetics behavior.In view of the limitations of the isoconversional methods for studying complex kinetic processes,it is necessaiy to further explore the effect of alcohols on the thermal denaturation of collagen by using the model-fitting methods.

关 键 词：胶原 热变性动力学 无模式函数法 甘油 异丙醇 

分 类 号：TS51[轻工技术与工程—皮革化学与工程]