温针灸治疗糖尿病足筋疽0级微炎症的临床疗效  

Clinical Effects of Warm Needling Moxibustion in the Treatment for Diabetic Foot Gangrene Level Zero Microinflammation

作　　者：郑明岳 张磊[3] 吴耀持[2] ZHENG Mingyue;ZHANG Lei;WU Yaochi(Shanghai University of TCM,Shanghai 201203,China;The 6th People′s Hospital Affiliated to Shanghai Jiaotong University;Shanghai Shuguang Hospital Affiliated with Shanghai University of TCM)

机构地区：[1]上海中医药大学,上海201203 [2]上海市第六人民医院 [3]上海中医药大学附属曙光医院

出　　处：《西部中医药》2019年第9期41-44,共4页Western Journal of Traditional Chinese Medicine

摘　　要：目的:观察温针灸治疗糖尿病足筋疽0级微炎症的临床疗效。方法:将糖尿病足筋疽潜证患者63例根据随机、对照原则分为对照组32例、治疗组31例。2组均进行基础治疗,治疗组同时行温针灸治疗,每日1次,连续治疗7天。比较2组患者临床症状及微炎症指标变化情况。结果:治疗组治愈0例(0.0%),显效5例(16.1%),有效25例(80.6%),无效1例(3.2%);对照组治愈0例(0.0%),显效2例(6.3%),有效28例(87.5%),无效2例(6.3%)。2组临床疗效比较差异有统计学意义(Z=-2.133,P=0.033);2组治疗后组间比较肿瘤坏死因子α(TNF-α)、超敏C反应蛋白(hs-CRP)差异具有统计学意义(P<0.05);2组治疗前后CRP、降钙素原、白细胞介素2、白细胞介素6、白细胞介素8、免疫球蛋白比较差异无统计学(P>0.05)。结论:温针灸加基础治疗能降低糖尿病足筋疽0级患者TNF-α、hs-CRP水平,改善患者的微炎症状态,降低出现肢体破溃的风险,效果优于单纯基础治疗。Objective: To observe clinical effects of warm needling moxibustion in the treatment for diabetic foot gangrene level zero microinflammation. Methods: All 63 potential patients suffering diabetic foot gangrene were divided to 32 cases of the control group and 31 cases of the treatment group according to random control principle.Both groups performed basic therapy, the treatment group were treated by warm needling moxibustion, once each day, for seven consecutive days. To compare clinical symptoms and microinflammation indexes between both groups. Results: There was zero case cured(0.0%), five cases markedly effective(16.1%), 25 cases effective(80.6%)and one case ineffective(3.2%) in the treatment group;zero case cured(0.0%), two cases markedly effective(6.3%),28 cases effective(87.5%) and two case ineffective(6.3%) in the control group. The difference had statistical meaning in clinical effects between both groups(Z=-2.133, P=0.033). The difference could be found in the levels of TNF-αand hs-CRP between both groups after treating(P<0.05). The difference had no statstical meaning in the comparison of CRP, PCT, IL-2, IL-6, IL-8 and immunoglobulin before and after treating between both groups(P>0.05). Conclusion:Warm needling moxibustion and basic therapy could reduce the levels of TNF-α and hs-CRP, improve microinflammation state and decrease the risk of limb ulceration in the treatment for diabetic foot gangrene level zero microinflammation, and its effects are superior to these of single basic therapy.

关 键 词：糖尿病足 筋疽 微炎症 温针灸 

分 类 号：R259[医药卫生—中西医结合]