正念对乳腺癌化疗患者情绪和生活质量的影响  

Effects of mindfulness on affections and quality of life among breast cancer patients in chemotherapy

作　　者：单墨水 赵忠凯 杨毅 杨俊兰[2] 王建东[2] 苏彤 Shan Moshui;Zhao Zhongkai;Yang Yi(Department of Psychiatry,Lieningjie Section of PLA No.967 Hospital,Dalian 116041,China)

机构地区：[1]解放军967医院列宁街院区,大连116041 [2]解放军总医院 [3]海军军医大学心理系医学心理学教研室

出　　处：《中华保健医学杂志》2019年第5期400-404,共5页Chinese Journal of Health Care and Medicine

基　　金：国家自然科学基金（81602734）;国家科技支撑计划项目(2013BAI08B03)

摘　　要：目的探讨正念对乳腺癌化疗患者情绪及生活质量的影响。方法选取解放军总医院招募的90名乳腺癌化疗患者,按随机数表法分为干预组和对照组,每组45例。干预组共给予8次正念治疗,每次1.5 h,其余时间患者在家自行练习,每日至少15 min。对照组试验期内给予常规治疗和护理。两组均在第0周(T0)、第6周末(T1)、第12周末(T2)进行广泛性焦虑量表(GAD-7)、患者健康问卷抑郁量表(PHQ-9)及EORTC生命质量测查表(QLQ-C30)测量,采用SPSS 18.0统计软件进行数据分析。结果干预组抑郁、躯体功能、情感功能、认知功能、社会功能、疲乏得分较对照组均显著改善,差异有统计学意义(P<0.05);干预组GAD-7、PHQ-9、总体健康状况、躯体功能、角色功能、情感功能、认知功能、社会功能、疲乏、疼痛、失眠得分T1较T0均显著改善,差异有统计学意义(P<0.01),且在随访期内疗效维持;对照组PHQ-9、角色功能、情感功能、疼痛得分T1与T0比较,差异有统计学意义(P<0.05);PHQ-9、总体健康状况、躯体功能、角色功能、情感功能、社会功能、疼痛、失眠得分T2与T0比较,差异有统计学意义(P<0.05)。结论正念对于改善乳腺癌患者情绪和生活质量疗效显著,可以在医院推广应用。Objective To evaluate the effects of mindfulness on anxiety,deression and quality of life in patients with breast cancer chemotherapy and explore available psychological intervention scheme.Methods 90 breast cancer patients recruited were divided into randomly mindfulness group and control group.Mindfulness group received 8 times in mindfulness training during hospitalization,and conducted at least fifteen-minute home practice everyday.Regular therapy and care were conducted for control group without psychotherapy.All subjects were assessed with GAD-7,PHQ-9 and EORTC QLQ-C30 at three time points(before chemotherapy,end of the 6th week and end of the 12th week).All data was analyzed with Spss 18.0 statistical package.Results Depression,physical functioning,emotional functioning,cognitive functioning,fatigue in mindfulness group improved significantly compared to control group(P<0.05).GAD-7,PHQ-9,global health status,,physical functioning,role functioning,emotional functioning,congnitive functioning,social functioning,fatigue,pain and insomnia in mindfulness group improved significantly at T1 compared to T0(P<0.01),and effects persisted at T2.In control group depression,role functioning,emotional functioning and pain improved significantly at T1(P<0.05),and depression,global health status,physical functioning,role functioning,emotional functioning,social functioning,pain and insomnia at T2 improved significantly compared to T0(P<0.05).Conclusion Mindfulness had positive effects on improving mental symptoms and quality of life among breast cancer patients in chemotherapy,which should be applied in the hospital.

关 键 词：乳腺癌 正念 心理治疗 

分 类 号：R395.1[哲学宗教—心理学]